A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1.

Abstract

A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose transport activity. Restoration of gltR resulted in wild-type levels of glucose transport. These findings indicate that gltR is required for expression of the glucose transport system in P. aeruginosa. Originally published Journal of Bacteriology, Vol. 178, No. 20, Oct 1996