A case of Exophiala oligosperma successfully treated with voriconazole
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Rimawi, Bassam H.
Rimawi, Ramzy H.
Mirdamadi, Meena
Steed, Lisa L.
Marchell, Richard
Sutton, Deanna A.
Thompson, Elizabeth H.
Wiederhold, Nathan P.
Lindner, Jonathan R.
Boger, M. Sean
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Abstract
Exophiala oligosperma is an uncommon pathogen associated with human infections, predominantly in immunocompromised hosts. Case reports of clinical infections related to E. oligosperma have been limited to 6 prior publications, all of which have shown limited susceptibility to conventional antifungal therapies, including amphotericin B, itraconazole, and fluconazole. We describe the first case of an E. oligosperma induced soft-tissue infection successfully treated with a 3-month course of voriconazole without persisting lesions.
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10.1016/j.mmcr.2013.08.003