Systematic review of diagnostic tests for vaginal trichomoniasis.
dc.contributor.author | Patel, Sangnya R. | en_US |
dc.contributor.author | Wiese, Wilhelmine | en_US |
dc.contributor.author | Patel, Sanjay C. | en_US |
dc.contributor.author | Ohl, Christopher | en_US |
dc.contributor.author | Byrd, James C. | en_US |
dc.contributor.author | Estrada, Carlos A. | en_US |
dc.date.accessioned | 2011-04-28T14:32:09Z | en_US |
dc.date.accessioned | 2011-05-17T00:25:39Z | |
dc.date.available | 2011-04-28T14:32:09Z | en_US |
dc.date.available | 2011-05-17T00:25:39Z | |
dc.date.issued | 2000 | en_US |
dc.description.abstract | Objective: To review critically and to summarize the evidence of diagnostic tests and culture media for the diagnosis of Trichomonas vaginitis. Methods: We performed a systematic review of literature indexed in MEDLINE of studies that used Trichomonas culture as the reference standard (9,882 patients, 35 studies). Level I studies (5,047 patients, 13 studies) fulfilled at least two of three criteria: 1) onsecutive patients were evaluated prospectively, 2) decision to culture was not influenced by test results, and 3) there was independent and blind comparison to culture. Results: The sensitivity of the polymerase chain reaction technique (PCR) was 95% (95% CI 91% to 99%), and the specificity was 98% (95% CI 96% to 100%). One study was classified as Level I evidence (52 patients). The sensitivity of the enzyme-linked immunosorbent assay was 82% (95% CI 74% to 90%), and the specificity was 73% (95% CI 35% to 100%). The sensitivity of the direct fluorescence antibody was 85% (95% CI 79% to 90%), and the specificity was 99% (95% CI 98% to 100%). Sensitivities of culture media were 95% for Diamond’s, 96% for Hollander, and 95% for CPLM. Conclusions: The sensitivity and specificity of tests to diagnose trichomoniasis vary widely. Originally published Infectious Diseases in Obstetrics and Gynecology, Vol. 8, No. 5-6, 2000 | en_US |
dc.identifier.citation | Infectious Diseases in Obstetrics and Gynecology; 8:5-6 p. 248-257 | en_US |
dc.identifier.pmid | PMC1784697 | en_US |
dc.identifier.uri | http://hdl.handle.net/10342/3375 | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | East Carolina University | en_US |
dc.relation.uri | http://www.hindawi.com/journals/idog/ | en_US |
dc.rights | Author notified of opt-out rights by Cammie Jennings prior to upload of this article. | en_US |
dc.subject | Diagnosis | en_US |
dc.subject | Evidence-based medicine | en_US |
dc.subject | Meta-analysis | en_US |
dc.subject | Sensitivity and specificity | en_US |
dc.subject | Trichomonas | en_US |
dc.title | Systematic review of diagnostic tests for vaginal trichomoniasis. | en_US |
dc.type | Article | en_US |
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