Biophysical Mechanisms Mediating Fibrin Fiber Lysis
| dc.contributor.author | Hudson, Nathan E. | |
| dc.date.accessioned | 2017-06-09T19:06:29Z | |
| dc.date.available | 2017-06-09T19:06:29Z | |
| dc.date.issued | 2017-05-28 | |
| dc.description.abstract | The formation and dissolution of blood clots is both a biochemical and a biomechanical process. While much of the chemistry has been worked out for both processes, the influence of biophysical properties is less well understood. This review considers the impact of several structural and mechanical parameters on lytic rates of fibrin fibers. The influences of fiber and network architecture, fiber strain, FXIIIa cross-linking, and particle transport phenomena will be assessed. The importance of the mechanical aspects of fibrinolysis is emphasized, and future research avenues are discussed. | en_US |
| dc.description.sponsorship | ECU Open Access Fund | en_US |
| dc.identifier.citation | Nathan E. Hudson, “Biophysical Mechanisms Mediating Fibrin Fiber Lysis,” BioMed Research International, vol. 2017, Article ID 2748340, 17 pages, 2017. doi:10.1155/2017/2748340 | en_US |
| dc.identifier.doi | https://doi.org/10.1155/2017/2748340 | |
| dc.identifier.uri | http://hdl.handle.net/10342/6225 | |
| dc.language.iso | en_US | en_US |
| dc.relation.uri | https://www.hindawi.com/journals/bmri/2017/2748340/ | en_US |
| dc.subject | Fibrin fibers | en_US |
| dc.subject | Lytic rates | en_US |
| dc.subject | Blood clots | en_US |
| dc.subject | Biophysical mechanisms | en_US |
| dc.title | Biophysical Mechanisms Mediating Fibrin Fiber Lysis | en_US |
| dc.type | Article | en_US |
| ecu.journal.issue | Article ID 2748340 | en_US |
| ecu.journal.name | BioMed Research International | en_US |
| ecu.journal.pages | 1-17 | en_US |
| ecu.journal.volume | 2017 | en_US |
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