Browsing by Title
Now showing items 2272-2291 of 10620
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Deep Sequencing Reveals Transcriptome Re-Programming of Taxus × media Cells to the Elicitation with Methyl Jasmonate
(2013-04-30)Background Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. ... -
Defend Your Coast: Network Analysis of Crusader Fortifications and Settlements Within the Kyrenia Region of Cyprus
(East Carolina University, 2019-04-26)The Mediterranean island of Cyprus is situated at the crossroads of the Near East and the Aegean Civilizations. During the Middle Ages, Cyprus experienced raids that would devastate the coastal landscape. Coastal towns and ... -
Defending Diversity: Affirmative Action and Medical Education
(East Carolina University, 1999-08)Affirmative action programs of all types are under attack legally and politically. Although medical schools have not been specifically targeted, their affirmative action programs, like others in higher education, are ... -
Defending the East Coast : Adapting and Converting Commercial Ships for Military Operations
(East Carolina University, 2015)The United States was not fully prepared for war in the Atlantic Ocean directly after the bombing of Pearl Harbor on 7 December 1941. Closely following the attack, Germany declared war on the United States and Hitler's ... -
A Defense of Rational Choice as a Meaningful Baseline in Natural Resource and Hazard Economics
(2012-03-29)RCAW Five Year Achievement Award -
Deficiency of a Sinorhizobium meliloti bacA Mutant in Alfalfa Symbiosis Correlates with Alteration of the Cell Envelope
(East Carolina University, 2002-10)The BacA protein is essential for the long-term survival of Sinorhizobium meliloti and Brucella abortus within acidic compartments in plant and animal cells, respectively. Since both the S. meliloti and B. abortus bacA ... -
Defining B-29 Airscapes in the Archaeological Record as a Predictive Model for Site Location
(East Carolina University, 2018-04-27)The Boeing B-29 Superfortress made history when it dropped atomic bombs on Hiroshima and Nagasaki, Japan, bringing an end to World War II. Based on a small island in the central Pacific Ocean, this colossal aircraft left ... -
Defining Eastern North Carolina Upriver Steamboats Through Tar River Archaeology and History
(East Carolina University, 2012)This thesis will identify the salient features of North Carolina upriver steamboats and their relationships to steamboats from a variety of regions in the United States in an effort to understand the means by which people ... -
Defining God, Love, and Grammar
(East Carolina University, 2014)Based on textual research and general discussion in academia, a field-accepted definition of grammar for the purposes of first-year writing does not yet exist. In order to provide a working definition of grammar, forty-six ... -
Defining Protein Motions the Comprise the Reaction Barrier in Human Epithelial 15-Lipoxygenase-2
(East Carolina University, 2022-04-27)Proteins are dynamic in nature, with these motions playing a role in substrate binding and product release. Protein thermal motions have emerged as participating in the bond making/breaking steps of catalysis and by extension ... -
DEFINING THE ABILITY OF SNAT NANOTHERAPEUTIC TO INHIBIT SARS-COV-2 INFECTION AND ALTER THE HOST MICRONOME TO INDUCE AN ANTIVIRAL CELLULAR ENVIRONMENT
(East Carolina University, 2023-12-07)MicroRNAs (miRNAs) are regulatory elements that canonically bind to target mRNAs, reducing translation and protein output. They are non-coding strands of RNA, roughly 18-25 nucleotides long, and are found in plants, animals, ... -
Defining the Great Lakes Passenger Freight Propeller: A Statistical, and Historical Study
(East Carolina University, 2018-12-06)Passenger freight propellers were integral to the Great Lakes economy for nearly 100 years. A unique vessel type created for a unique need, shipbuilders combined different new technologies to create faster, more efficient, ... -
Defining the role of acyl-CoA synthetase 6 on α-synucleinopathy
(East Carolina University, 2022-07-19)Background: Neurodegenerative diseases known as [alpha]-synucleinopathies, most notably dementias and Parkinson's Disease (PD), are characterized by neuronal aggregation and accumulation of [alpha]-synuclein ([alpha]-syn) ... -
Defining the role of acyl-CoA synthetase 6 on α-synucleinopathy
(East Carolina University, 2022-07-19)Background: Neurodegenerative diseases known as α-synucleinopathies, most notably dementias and Parkinson’s Disease (PD), are characterized by neuronal aggregation and accumulation of α-synuclein (α-syn) in a manner that ... -
Defining the Role of the C-Terminal Region of Troponin T by Analysis of a Series of Truncation Mutants
(East Carolina University, 2016-07-21)Familial hypertrophic cardiomyopathy and other cardiovascular diseases result from mutations of any of the contractile proteins. Mutations within the actin binding regulatory complex of proteins, including tropomyosin (Tm) ... -
DEFINING THE STRATIGRAPHIC AND PALEOENVIRONMENTAL RECORD OF RAPID SEA-LEVEL RISE DURING THE LATE PLEISTOCENE TO HOLOCENE IN THE ALBEMARLE SOUND REGION OF NORTH CAROLINA
(East Carolina University, 2022-08-19)Sea-level fluctuations throughout the late Quaternary Period are recorded in the shallow stratigraphy and modern geomorphology of coastal North Carolina. In the Albemarle Sound region, four distinct Pleistocene sea-level ... -
DEFINING THE STRATIGRAPHIC AND PALEOENVIRONMENTAL RECORD OF RAPID SEA-LEVEL RISE DURING THE LATE PLEISTOCENE TO HOLOCENE IN THE ALBEMARLE SOUND REGION OF NORTH CAROLINA
(East Carolina University, 2022-08-19)We need to replace the abstract. -
The Definition of the Work Entity for Pieces of Recorded Sound
(2015-10)The traditional work-instance model differentiates between the intellectual content of a work and the semantic content of its material instantiations. Most scholarship on musical works has concentrated on classical music ...