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An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects.
(East Carolina University, 1988-08)
We have developed an in vitro muscle preparation suitable for metabolic studies with human muscle tissue and have investigated the effects of obesity and non-insulin-dependent diabetes mellitus (NIDDM) on glucose transport. ...
Long-term effect of insulin on glucose transport and insulin binding in cultured adipocytes from normal and obese humans with and without non-insulin-dependent diabetes.
(East Carolina University, 1987-10)
We have tested the hypothesis that in vitro exposure of insulin-
resistant adipocytes with insulin results in improved insulin
action. A primary culture system of adipocytes from obese
subjects with ...
Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver.
(East Carolina University, 1988-04)
Insulin-like growth factor-I (IGF-I) in human hepatoma cells
(HEP-G2) has, in addition to its effect on cell growth, shortterm
metabolic effects acting through its own receptor. We
have demonstrated that normal ...
Is type II diabetes mellitus (NIDDM) a surgical disease?
(East Carolina University, 1992-06)
Since February 1, 1980, 515 morbidly obese patients have undergone
the Greenville gastric bypass (GGB) operation. Of these,
212 (41.2%) were euglycemic, 288 (55.9%) were either diabetic
or had glucose intolerance, and ...