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The Role of eIF4G-1 Isoforms and Live Cell Imaging of IRES-mediated Translation Initiation in Breast Cancer Cells
(East Carolina University, 2012)
The development of cancer is a consequence of mutations that lead to dysfunctional cell processes such as unrestrained cell proliferation, resistance to apoptosis, and improper regulation of cell processes such as translation. ...
Assessing Parenting Behaviors of a Southern, Rural Community Using the Ghent Parental Behavior Scale
(East Carolina University, 2012)
This study was conducted to examine parental behaviors of a southern, rural community and what demographics are related to certain parenting behaviors. Archival data were used from a sample of high school parents (N = 39) ...
Elucidating the Mechanism of Action of Unnatural Amino Acid Containing Antimicrobial Peptides in Membrane Environments
(East Carolina University, 2012)
Organism resistance continues to develop to the currently available antimicrobial compounds necessitating the development of innovative new therapeutic compounds with different specificities and mechanisms of action that ...
NADPH Oxidase as a Mechanistic Link Between Erectile Dysfunction, Peripheral, and Coronary Endothelial Dysfunction in Obesity
(East Carolina University, 2012)
Cardiovascular complications involving both microvascular and macrovascular tissues are the major cause of morbidity and mortality in obese patients. Clinical and epidemiological studies suggest that erectile dysfunction ...
BRACTEATES AS INDICATORS OF NORTHERN PAGAN RELIGIOSITY IN THE EARLY MIDDLE AGES
(East Carolina University, 2012)
This thesis investigates the religiosity of some Germanic peoples of the Migration period (approximately AD 300-800) and seeks to overcome some difficulties in the related source material. The written sources which describe ...
Narrative, Identity, and Sense of Place Discourse : Woman's Club of Fayetteville, North Carolina, 1906-1912
(East Carolina University, 2012)
This dissertation analyzes the discourse (the narratives) used by members of the Woman's Club of Fayetteville in Fayetteville, North Carolina, from 1906 through 1912, as they (1) saved the Market House from destruction and ...
EXAMINING THE INSTRUCTIONAL UTILITY OF CURRICULUM BASED MEASUREMENT IN ACHIEVEMENT EVALUATIONS
(East Carolina University, 2012)
The purpose of this study is to expand the current research on the usefulness of CBM reports in the schools. Specifically, we wanted to study the types of information included in typical achievement reports and how much ...
One Day Your Ship Will Come In
(East Carolina University, 2012)
My thesis is called One Day Your Ship Will Come In and consists of several pieces of fiction. The setting of most of these pieces is deliberately vague for aesthetic reasons, but any reader inclined to investigate can ...
THE RETURN
(East Carolina University, 2012)
"The Return" investigates how culture shapes our understanding of the natural world. The life process of death is the key to this understanding. Culture has interpreted, compartmentalized, or rationalized this process in ...
Molecular Mechanisms of Peripheral N-Methyl-D-Aspartate Mediated Pressor Response
(East Carolina University, 2012)
The primary goal of this study was to characterize the N-Methyl-D-Aspartate (NMDA) receptor within the cardiovascular system and elucidate the molecular mechanisms involved in peripheral NMDA receptor-mediated pressor ...