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Peroxisomal-Mitochondrial Metabolic Interactions in Lipid Metabolism in Human Skeletal Muscle
(East Carolina University, 2016-11-16)
Peroxisomal activity and associated functions, including [beta]-oxidation contributions toward maintaining cellular lipid homeostasis, is poorly defined in extra hepatic tissues, most especially in human skeletal muscle ...
Exposure to Heat Stress, Solar Ultraviolet Radiation and Other Occupational Health Hazards Among Groundskeepers at East Carolina University
(2016-09-26)
Groundskeepers work most of the year outdoors, performing physically demanding duties. The amount of time spent working outdoors exposes groundskeepers to various hazards including physical hazards (hot temperatures, cold ...
Environmental Health: Food Safety
(2016-09-26)
NOVEL MECHANISMS GOVERNING SKELETAL MUSCLE MITOCHONDRIAL BIOENERGETICS : OXPHOS EFFICIENCY AND cAMP/PKA SIGNALING
(East Carolina University, 2014)
Understanding the regulation of cellular metabolism is paramount to treating the growing prevalence of metabolic disease worldwide. In cellular metabolism, mitochondrial oxidative phosphorylation (OXPHOS) plays a key role ...
Effects of High-Insulin Exposure on Mitochondrial Content in Skeletal Muscle Myotubes from Lean & Severely Obese Individuals: A Time Course Analysis
(East Carolina University, 2016-08-01)
Skeletal muscle is the site at which highly regulated energetic processes take place as a means of maintaining both tissue-specific and whole-body metabolism. With the development of severe obesity (BMI [greater-than] or ...
Substrate Utilization During Submaximal Exercise in Children with a Severely Obese Mother and Response to Exercise Training
(East Carolina University, 2016-08-18)
The aim of this study was to compare fat metabolism during submaximal exercise in children with a severely obese mother (BMI[greater than or equal to]35 kg/m2) to children with a lean, non-obese mother (BMI[less than or ...
Noise Exposure Assessment among Groundskeepers: A Pilot Study
(2016-09-26)
Purpose of the Study
•To assess and investigate the noise exposure, the associated hearing effects and the use of hearing protection devices (HPDs) among groundskeepers at East Carolina University (ECU)
•Hypothesis (H0): ...
Attachment-Based Treatment for Pediatric Obesity in Integrated Behavioral Health Care
(East Carolina University, 2016-12-16)
Pediatric obesity is a growing health concern afflicting the United States. Pediatric obesity, as a health epidemic, not only costs billions of dollars to our nation, but also negatively impacts the biological, psychological, ...
ELUCIDATION ON THE MECHANISM OF CAMKKα AS A PRO-GROWTH KINASE IN MOUSE SKELETAL MUSCLE
(East Carolina University, 2016-12-15)
Type 2 diabetes affects ~25 million people in the U.S., and is the primary cause of non-traumatic lower limb amputation and the leading cause of blindness in adults. Major risk factors for the development of type 2 diabetes ...
The Role of Hope with School Aged Children
(East Carolina University, 2016-12-15)
Hope has been defined as "the sum of perceived capabilities to produce routes to desired goals, along with the perceived motivation to use those routes" (Snyder, 2000 p. 8). Hope has the potential to influence several ...