Author | Gordon, Scott Edward | en_US |
Author | Lake, Jordan A. | en_US |
Author | Westerkamp, Christopher M. | en_US |
Author | Thomson, David M. | en_US |
Date Accessioned | 2010-11-17T19:56:02Z | en_US |
Date Accessioned | 2011-05-16T20:40:46Z | |
Date Available | 2010-11-17T19:56:02Z | en_US |
Date Available | 2011-05-16T20:40:46Z | |
Date of Issue | 2008-10 | en_US |
Identifier (Citation) | Exercise and Sports Sciences Reviews; 36:4 p. 179-186 | en_US |
Identifier (URI) | http://hdl.handle.net/10342/3009 | en_US |
Description | The activity of 5'-adenosine monophosphate–activated protein kinase, a negative regulator of cell size, is up-regulated with age in resting and overloaded fast-twitch skeletal muscle but not slowtwitch muscle. Here, we provide evidence to support the hypothesis that elevated 5'-adenosine monophosphate–activated protein kinase activity plays a potentially important integrative role in the age-related atrophy and diminished capacity for growth specific to fast-twitch skeletal muscle. Originally published in Exercise and Sports Sciences Reviews 2008 Vol. 36, No. 4. | en_US |
Language | en_US | en_US |
Publisher | East Carolina University | en_US |
Related URI | http://journals.lww.com/acsm-essr/toc/2008/10000 | en_US |
Rights | Author notified of opt-out rights by Kent Nixon Myers prior to upload of this article. | en_US |
Subject | Sarcopenia | en_US |
Subject | Aging | en_US |
Subject | Loading | en_US |
Subject | Hypertrophy | en_US |
Subject | Fiber type | en_US |
Subject | Translation | en_US |
Subject | Protein synthesis | en_US |
Title | Does AMP-Activated Protein Kinase Negatively Mediate Aged Fast-Twitch Skeletal Muscle Mass? | en_US |
Type | Article | en_US |
Identifier (PMID) | PMC2659413 | en_US |
Identifier (DOI) | 10.1097/JES.0b013e3181877e13 | |
Journal Name | Exercise and Sports Sciences Reviews | |
Journal Volume | 36 | |
Journal Issue | 4 | |
Article Pages | 179-186 | |