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Now showing items 11-20 of 63
INVESTIGATING THE EFFECTS OF LARVAL PHENOTYPES ON TRAITS EXHIBITED AT A CRUCIAL LIFE-HISTORY SWITCH POINT
(East Carolina University, 2017-07-25)
In organisms with complex life histories, phenotypes exhibited in non-reproductive life stages are often correlated with adult performance and fitness. For example, in anurans (frogs and toads), age and size at metamorphosis ...
The Effect of Visual Queues on Social Status Formation and Mauthner Sensitivity in Zebrafish
(East Carolina University, 2017-04-27)
Zebrafish of the TLN strain, a genetic variant of the Tüpfel Long-fin (TL) wild-type zebrafish that does not display the trademark striped scale pattern of wild-type zebrafish, but are instead pale, were tested through a ...
Breathing New Life into Philosophical Inquiry through the Use of Fiction
(East Carolina University, 2017-05-03)
To incite every day people to venture into the world of philosophical thought and intrigue, I have constructed the beginnings of a novel that will use the old allegories and ideas of the past and place them into a new ...
Characterizing Multigenerational Effects of Nicotine-Dependent Behaviors in Caenorhabditis Elegans
(East Carolina University, 2017-05-03)
This project aims to investigate the effects nicotine, a highly addictive chemical associated with tobacco smoking, have on offspring (F1 and F2) using the model organism Caenorhabditis elegans (C. elegans). C. elegans is ...
Implementing a high sensitivity point-of-care troponin assay is beneficial in an emergency department chest pain population
(East Carolina University, 2017-05-03)
Point of care tests (POC) can provide accurate and more rapid results for physicians at the bedside, thus decreasing the patient’s time to treatment and increasing patient prognosis. Cardiac troponin (cTnI) is the leading ...
HUMAN T-CELL LEUKEMIA VIRUS TYPE 1-ENCODED PROTEIN HBZ INCREASES VIRAL INFECTION
(East Carolina University, 2017-05-04)
Human T-lymphotropic virus type 1 (HTLV-1) is a complex retrovirus, infecting CD4+ T lymphocytes. About 10 million people worldwide are infected with HTLV-1. HTLV-1 has been linked to adult T-cell leukemia (ATL), a disease ...
The Role of Pre-Replication Complex Proteins in Drosophila Ovarian Stem Cell Maintenance and Proliferation
(East Carolina University, 2017-05-05)
Cancer stem cells (CSCs) may hold the key to advances in cancer research. Like adult tissue-specific stem cells, CSCs are able to self-renew and last a lifetime. These shared characteristics can thus be used to help learn ...
INVESTIGATING THE MOLECULAR CONTROL OF ECDYSONE RESPONSE GENE, E74, IN THE DROSOPHILA OVARY.
(East Carolina University, 2017-05-05)
Oogenesis is the process by which an egg develops from precursor cells in the ovary. This process has been widely studied; however, many of the molecular mechanisms that regulate oocyte development and growth remain unclear. ...
Prevention of synaptic loss in cortico-hippocampal culture by silencing Kremen1 with siRNA
(East Carolina University, 2017-05-19)
Research has shown that Alzheimer’s disease could be a result of an accumulation of amyloid β (Aβ) plaques and tau protein. The accumulation of Aβ activates p53, which leads to an increase of Dickkopf-1 (Dkk1). When Dkk1 ...