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The effects of environmental nickel toxicity upon survival, growth, reproduction, fecundity, and lifespan of nematodes Caenorhabditis elegans, Pristionchus pacificus, and Caenorhabditis briggsae
(East Carolina University, 2012)
Nickel (II) is a common component of many natural products and man-made devices. Due to its frequent use in everyday life, relatively large amounts of nickel are being released into the environment. Nickel, however, is a ...
DEHP Impairs Zebrafish Reproduction by Affecting Critical Factors in Oogenesis
(East Carolina University, 2010-04-15)
Public concerns on phthalates distributions in the environment have been increasing since they can cause liver cancer, structural abnormalities and reduce sperm counts in male reproductive system. However, few data are ...
Effects of 5-fluorouracil Drug Treatment on the Expression Profile of MicroRNAs in MCF7 Breast Cancer Cells
(East Carolina University, 2010)
Breast cancer is one of the leading causes of deaths in women worldwide. 5-flourouracil (5-FU) is a classic chemotherapeutic drug that has been widely used in the treatment of breast cancer patients. In this study, using ...
Coevolutionary analysis of Appalachian Xystodesmid millipedes and their symbiotic Mesostigmatid mites
(East Carolina University, 2010)
Mites (Acari) form symbiotic relationships with many animal taxa including fish, amphibians, reptiles, birds, mammals, mollusks, and arthropods. They are frequently found living on millipedes, and it has often been ...
Consequences of Reduced Versican Expression in Embryonic Chick Synovial Joint Development
(East Carolina University, 2012)
The different mechanisms involved in vertebrate synovial joint development are actively being uncovered. A variety of studies have thus far discovered the involvement of several large molecules in the processes of joint ...
Multiple Factors Influence the Strength of Intraguild Interactions
(East Carolina University, 2011)
Species engaged in intraguild predation (IGP) not only compete for the same food resources but can also eat each other. In some cases, a predator species in a higher trophic position (i.e., a top predator) can eat a ...
ESTABLISHING LINKAGE BETWEEN GINS COMPLEX SUB-UNIT Sld5 AND CHECKPOINT PROTEIN Chk2 (loki) USING DROSOPHILA MELANOGASTER AS MODEL ORGANISM
(East Carolina University, 2012)
Eukaryotic DNA replication is controlled by a number of proteins that ensures the process takes place accurately. GINS, a hetero-tetrameric protein complex is known to be essential for the initiation and progression of ...
Tumor Growth Induces Oxidative Clustered DNA Lesions Damage in Distant Mouse Tissue in vivo
(East Carolina University, 2010)
Our goal was to ascertain if DNA damage induced by oxidative stress is capable of being exploited as a precancerous or cancer biomarker. The specific DNA damage that we assessed was oxidatively induced non-DSB clustered ...
DOES THE QUANTITY OF RESOURCES IN THE ENVIRONMENT ALTER THE IMPACT OF MULTIPLE PREDATORS ON THEIR PREY?
(East Carolina University, 2013)
Predation is an important biological process affecting prey populations and most prey in nature are exposed to multiple predator species. Much research has revealed that the combined effect of multiple predators on their ...
CAN NUTRIENT ADDITIONS MEDIATE GAPE LIMITED PREDATION IN LARVAL RANA SPHENOCEPHALA?
(East Carolina University, 2013)
Some predators are limited in the size prey item that they can catch and consume, and this is referred to as "gape limited". Prey found with these predators may have the ability to respond by growing rapidly to reach a ...