Search
Now showing items 31-40 of 54
Vectors of transmission: An early nicotine puff triggers a long-lasting microRNA molecular “memory” in C. elegans.
(East Carolina University, 2016-06-16)
The prevalence of passive and active nicotine exposure among neonates, children and adolescents remains relatively high and varies among cultures and countries. Currently, there is ample evidence that a safe nicotine dose ...
Exploring the roles of horizotnal gene transfer in metazoans
(East Carolina University, 2016-07-20)
Horizontal gene transfer (HGT; also known as lateral gene transfer, LGT) refers to the movement of genetic information between distinct species by overcoming normal mating barriers. Historically HGT is only considered to ...
Seasonal home range dynamics and sex differences in habitat use in a threatened, coastal marsh bird
(2016-12-22)
A comprehensive understanding of spatiotemporal ecology is needed to develop conservation strategies for declining species. The king rail (Rallus elegans) is a secretive marsh bird whose range historically extended across ...
ZOOPLANKTON COMMUNITY STRUCTURE AND ECOSYSTEM FUNCTION ACROSS A SALINITY GRADIENT
(East Carolina University, 2016-05-05)
Pre and post-colonization factors differentially affect community structure. Sea level rise is mixing formerly isoloted freshwater communities with salt water communities. These ponds have a large range of salinity, which ...
Climate Change Alters Trophic Interactions in Coastal Ecosystems
(East Carolina University, 2016-05-04)
Understanding the effects of multiple anthropogenic changes on local ecosystems is important for understanding community interactions. Because they lie at the interface between the land and sea coastal ecosystems are often ...
Nickel as a mutagen and as an enabler of EMS genotoxicity in Caenorhabditis elegans
(East Carolina University, 2016-01-15)
Nickel is found naturally and vital for survival of some organisms. Nickel occurs as a metal as insoluble compounds and soluble compounds. Nickel exposure has increased due to urbanization from various sources including ...
Early Nicotine Exposure Altered Larval Neuromuscular Function and Adult Germline Apoptosis via MiRNA-Dependent Mechanisms
(East Carolina University, 2016-04-29)
MicroRNAs fine tune the expression of target genes needed for homeostasis. Our pilot study showed that nicotine altered 17% miRNAs in C. elegans larvae. Here, we investigated the role of microRNAs in mediating nicotine-induced ...
The effect of the Achilles tendon moment arm on knee joint contact force
(East Carolina University, 2016-04-29)
Musculoskeletal (MSK) models are used extensively in the study of human movement. The validity of a given MSK model is affected by the architectural features of the system. The Achilles tendon moment arm is one important ...
A validated protocol to quantify severity of male urogenital feminization using the MOUSE (Mouse objective urethral severity evaluation)
(2016-06-13)
Background
Congenital abnormalities vary in presentation, yet studies using model organisms tend to focus on occurrence rather than severity of the defect. Scoring severity of abnormalities in model systems allows explicit ...
Characterizing the role of the Early Gene at 23 (E23) in Drosophila Melanogaster Oogenesis
(East Carolina University, 2016-04-29)
Drosophila melanogaster (fruit fly) females undergo oogenesis to create oocytes from undifferentiated stem cells in the ovary. Similar to estrogen in humans, the steroid hormone ecdysone in fruit flies has a known role in ...