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Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor
(East Carolina University, 2003-03-04)
Recently we discovered a previously uncharacterized gene with the characteristics of a membrane progestin receptor (mPR) in a fish model, spotted seatrout. Here, we report the identification, cloning, and characteristics ...
Processing of bistranded abasic DNA clusters in γ-irradiated human hematopoietic cells
(East Carolina University, 2004)
Clustered DNA damages—two or more lesions on opposing strands and within one or two helical turns—are formed in cells by ionizing radiation or radiomimetic antitumordrugs. They are hypothesized to be difficult to repair, ...
Visual mate choice in poison frogs.
(East Carolina University, 1999-11-07)
We investigated female mate choice on the basis of visual cues in two populations of Dendrobates pumilio, the strawberry poison frog, from the Bocas del Toro Archipelago in Panama, Central America. Mate choice experiments ...
DOES THE QUANTITY OF RESOURCES IN THE ENVIRONMENT ALTER THE IMPACT OF MULTIPLE PREDATORS ON THEIR PREY?
(East Carolina University, 2013)
Predation is an important biological process affecting prey populations and most prey in nature are exposed to multiple predator species. Much research has revealed that the combined effect of multiple predators on their ...
Evolution of the RNA polymerase II C-terminal domain
(East Carolina University, 2002-04-30)
In recent years a great deal of biochemical and genetic research has focused on the C-terminal domain (CTD) of the largest subunit (RPB1) of DNA-dependent RNA polymerase II. This strongly conserved domain of tandemly ...
CAN NUTRIENT ADDITIONS MEDIATE GAPE LIMITED PREDATION IN LARVAL RANA SPHENOCEPHALA?
(East Carolina University, 2013)
Some predators are limited in the size prey item that they can catch and consume, and this is referred to as "gape limited". Prey found with these predators may have the ability to respond by growing rapidly to reach a ...
Cardiac and Mitochondrial Adaptations in Response to Aging and Doxorubicin in Rats Bred for Divergent Aerobic Capacities
(East Carolina University, 2012)
Doxorubicin (DOX) remains as one of the most widely prescribed and effective anticancer agents. A major limitation of the therapeutic effectiveness of the drug is the occurrence of irreversible, progressive, dose-dependent ...
Effects of Modified Vaccinia Virus Ankara Expressing Mesothelin and the Poxvirus Immunoregulatory A35R gene in the Treatment of Murine Pancreatic Cancer
(East Carolina University, 2012)
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Pancreatic tumors over-express the protein mesothelin, and therefore, it is used as a tumor target antigen for vaccine development. ...
Bisphenol A: vom Saal and Hughes Respond
(East Carolina University, 2006-01)
Convergent evolution of bright coloration and toxicity in frogs
(East Carolina University, 2003-10-28)