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NMR characterizations of an amyloidogenic conformational ensemble of the PI3K SH3 domain
(East Carolina University, 2006-11)
Amyloid formation is associated with structural changes of native polypeptides to monomeric intermediate states and their self-assembly into insoluble aggregates. Characterizations of the amyloidogenic
intermediate state ...
Biimidazole diamide anion binding agents
(2006-07-18)
Biimidazole diamide compounds that are useful for binding anions such as sulfate are described, along with the use thereof for purposes such as extracting anions from a waste stream and/or detecting anions.
Tissue lockable connecting structures
(2006-08-01)
Percutaneous skin access devices include a plurality of locked connecting units mounted to the exterior surface of an implantable medical object which, in position, is configured to penetrate the skin of a subject. The ...