Browsing Physics by Type"Doctoral Dissertation"
Now showing items 21-37 of 37
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Ion Traffic Across Cellular Membranes
(East Carolina University, 2010)The cell membrane protects the delicate internal machinery of the cell and hosts a complex transport system for ion exchange with the environment. Energy is continually expended to maintain a transmembrane electrical ... -
Lèvy noise induced steady states
(East Carolina University, 2022-06-08)Systems far from equilibrium organize themselves to accommodate energy throughput. It is also in these nonequilibrium systems where noise has often been found to follow alpha-stable distributions, commonly called Lèvy ... -
Lèvy noise induced steady states
(East Carolina University, 2022-06-08)Systems far from equilibrium organize themselves to accommodate energy throughput. It is also in these nonequilibrium systems where noise has often been found to follow alpha-stable distributions, commonly called Lèvy ... -
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ... -
MODIFICATION OF CELL SURVIVAL RATES BY CERIUM OXIDE NANOPARTICLES FOR EXPOSURE TO PROTON RADIATION
(East Carolina University, 2017-05-03)Radiation therapy is a well-established and widely used treatment for a variety of malignancies in the human body. Current radiotherapy methods most frequently use x-rays to deliver a lethal dose to tumors with sufficient ... -
Optical and dielectric properties of metallic calcium, modeled generalized oscillator strength function of calcium, interaction cross sections of electrons, protons, and alpha particles with calcium
(East Carolina University, 2013)An analysis of the optical and the dielectric properties of calcium, determined from the literature, was performed. The optical functions of calcium were used for a calculation of the energy loss function of calcium. The ... -
Perturbation of Circadian Neuronal Oscillators with Low-Intensity Magnetic Stimulation
(East Carolina University, 2019-04-23)Circadian neuronal oscillatory dynamics are perturbed substantially in numerous neuropsychiatric diseases, such as Alzheimer's, Parkinson's, and depression. Moreover, desynchronization of neuronal oscillators complicates ... -
PROFILING EFFUSION CELLS BY QUANTITATIVE ANALYSIS OF MORPHOLOGY AND DIFFRACTION IMAGING PATTERNS
(East Carolina University, 2019-04-12)Profiling cells in human pleural and peritoneal effusion (PPE) samples is an essential task for cytological diagnosis of cancers and patient management. Conventional PPE cytology of a PPE sample is labor intensive and its ... -
A PROPOSED METHODOLOGY TO ASSESS HDR [superscript]192Ir RADIAL DOSE WITH FRICKE DOSIMETRY
(East Carolina University, 2011)The radial absorbed dose to water, D(r,theta), a quantity not yet directly measured with primary standards, was assessed with the Fricke solution which has been considered as an absolute aqueous solution to perform dosimetry. ... -
Protection and Sensitization of Human Cells to Proton Radiation by Cerium Oxide Nanoparticles
(East Carolina University, 2017-07-17)In radiation therapy for the treatment of cancer, there is demand for novel approaches that will improve tumor cell killing while protecting healthy tissue. One such approach that has shown considerable promise is the ... -
RADIOSENSITIZATION OF PROSTATE CARCINOMA CELLS BY PEGYLATED METALLIC NANOPARTICLES TO PROTON IRRADIATION
(East Carolina University, 2023-05-01)One of the main goals of cancer radiation therapy is to reduce the dose to healthy tissues while maximizing the dose to malignant tissue. A special class of materials known as "radiosensitizers" has emerged that can help ... -
SAFE HAVENS AND HOT SPOTS: IONIZING RADIATION IN MARTIAN PERMAFROST AND ITS INFLUENCE ON THE SURVIVAL OF ANCIENT LIFE
(East Carolina University, 2022-06-20)Permafrost on Mars is considered a primary target for the search for life. On a microscopic scale permafrost is highly non-uniform and the effective radiation dose absorbed by a microbe, and thus its survival probability, ... -
SAFE HAVENS AND HOT SPOTS: IONIZING RADIATION IN MARTIAN PERMAFROST AND ITS INFLUENCE ON THE SURVIVAL OF ANCIENT LIFE
(East Carolina University, 2022-06-20)Permafrost on Mars is considered a primary target for the search for life. On a microscopic scale permafrost is highly non-uniform and the effective radiation dose absorbed by a microbe, and thus its survival probability, ... -
Secondary Electron Emission Yields from Fast Fluorine Ions on Copper and Amorphous Solid Water Foils
(East Carolina University, 2011)The biological outcomes from charged particle radiation exposure are heavily influenced by the spatial patterns of energy distributed within the biological system. Monte Carlo track structure codes can be used to model ... -
Study of Morphology Based Cell Assay by Diffraction Imaging Flow Cytometry
(East Carolina University, 2015)Development of an accurate and label-free method for single cell assay attracts intensive research efforts for its importance to cell biology research and clinicG14G7al applications. Flow cytometry is one of the most widely ... -
The Effects of Low-Energy Heavy Charged Particles on the Optically Stimulated Luminescence and Thermoluminescence of Aluminum Oxide and Beryllium Oxide
(East Carolina University, 2021-06-02)Optically Stimulated Luminescence (OSL) and Thermoluminescence (TL) are methods utilized to evaluate the energy absorbed by crystalline insulators. It is necessary to test luminescent materials in a controlled environment ... -
VIABILITY OF CERIUM OXIDE NANOPARTICLES AS A RADIOPROTECTOR AGAINST PROTON RADIATION FOR NON-MALIGNANT CELLS
(East Carolina University, 2015)Radiation therapy is a prevalent cancer treatment therapy. The goal is to kill all tumor cells while minimizing damage to healthy cells and new methods that can accomplish this goal are continually being investigated. ...