Physics
Recent Submissions
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Uptake of and Resistance to the Antibiotic Berberine by Individual Dormant, Germinating and Outgrowing Spores as Monitored by Laser Tweezers Raman Spectroscopy
(2015-12)Article Authors Metrics Comments Related Content Abstract Introduction Materials and Methods Results Discussion Supporting Information Acknowledgments Author Contributions References Reader Comments (0) Media ... -
Label-free classification of cultured cells through diffraction imaging
(2011-05)Automated classification of biological cells according to their 3D morphology is highly desired in a flow cytometer setting. We have investigated this possibility experimentally and numerically using a diffraction imaging ... -
Memory of Germinant Stimuli in Bacterial Spores
(2015-11)Bacterial spores, despite being metabolically dormant, possess the remarkable capacity to detect nutrients and other molecules in their environment through a biochemical sensory apparatus that can trigger spore germination, ... -
In Vivo Blood Glucose Quantification Using Raman Spectroscopy
(2012)We here propose a novel Raman spectroscopy method that permits the noninvasive measurement of blood glucose concentration. To reduce the effects of the strong background signals produced by surrounding tissue and to obtain ... -
Kinetics of Germination of Individual Spores of as Measured by Raman Spectroscopy and Differential Interference Contrast Microscopy
(2013)Geobacillus stearothermophilus is a gram-positive, thermophilic bacterium, spores of which are very heat resistant. Raman spectroscopy and differential interference contrast microscopy were used to monitor the kinetics of ... -
VIABILITY OF CERIUM OXIDE NANOPARTICLES AS A RADIOPROTECTOR AGAINST PROTON RADIATION FOR NON-MALIGNANT CELLS
(East Carolina University, 2015)Radiation therapy is a prevalent cancer treatment therapy. The goal is to kill all tumor cells while minimizing damage to healthy cells and new methods that can accomplish this goal are continually being investigated. ... -
Considering the Oxygen Effect : Further Development of a Volumetric Model of Tumor Response to Radiation Therapy for Cervical Cancer
(East Carolina University, 2014)Mathematical modeling of tumor response to radiation therapy (RT) has great potential for designing therapy plans that are more personalized, more adaptive, and more reliable for outcome predictions. A preexisting model ... -
Correlating the Morphological and Light Scattering Properties of Biological Cells
(East Carolina University, 2013)The scattered light pattern from a biological cell is greatly influenced by the internal structure and optical properties of the cell. This research project examines the relationships between the morphological and scattering ... -
DOSIMETRIC STUDY OF BETA-MINUS EMITTER PRASEODYMIUM-142 : APPLICATIONS IN MICROSPHERE BRACHYTHERAPY FOR HEPATOCELLULAR CARCINOMA AND BRACHYTHERAPY FOR OCULAR SQUAMOUS CELL CARCINOMA
(East Carolina University, 2013)A dosimetric study of the beta-minus emitter Praseodymium-142 (¹⁴²Pr) was performed and two main innovative applications of this source in brachytherapy are proposed: microsphere brachytherapy and eye plaque brachytherapy. ... -
Development of a Finite Difference Time Domain (FDTD) Model for Propagation of Transient Sounds in Very Shallow Water
(2013-08-12)We developed a finite difference time domain (FDTD) model for sound propagation using pressure and velocity grids with both three-dimensional Cartesian and two-dimensional cylindrical implementations. Propagation parameters, ... -
COMPARISON OF TWO HUMAN CELL LINES FOLLOWING EXPOSURE TO LOW DOSE RADIATION AND TREATMENT WITH SOYBEAN MISO AND ITS ACTIVE INGREDIENT GENISTEIN
(East Carolina University, 2013)Exposure to radiation is increasingly becoming a worldwide health issue. Because of this, the need for effective radioprotectors is critical. This need is not met by amifostine, the current "gold standard" in radioprotectors, ... -
Optical and dielectric properties of metallic calcium, modeled generalized oscillator strength function of calcium, interaction cross sections of electrons, protons, and alpha particles with calcium
(East Carolina University, 2013)An analysis of the optical and the dielectric properties of calcium, determined from the literature, was performed. The optical functions of calcium were used for a calculation of the energy loss function of calcium. The ... -
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ... -
THE DESCRIPTION OF SCHUMANN ELECTROMAGNETIC RESONANCES BETWEEN EARTH AND ITS IONOSPHERE AS BOSE-EINSTEIN CONDENSATES OF EXTREMELY LOW FREQUENCY PHOTONS
(East Carolina University, 2012)The purpose of this thesis is to show that Schumann resonances between Earth and its ionosphere are Bose-Einstein condensates of extremely low frequency photons. We will show that the photon densities of the first five ... -
Analysis of Circular Dichroism and Linear Dichroism Spectroscopy
(East Carolina University, 2012)Circular Dichroism (CD) and Linear Dichroism (LD) spectroscopies measure the difference in absorption between left and right circularly polarized light and parallel and perpendicular linearly polarized light as a function ... -
COMPARATIVE ANALYSIS OF TWO HUMAN CANCER CELL LINES FOLLOWING EXPOSURE TO LOW DOSE RADIATION
(East Carolina University, 2011)Over the past two decades, studies on the cellular response to very low dose radiation have been revolutionizing historically-held paradigms of cellular radioresponse. Indeed, a host of seemingly contradictory events have ... -
A PROPOSED METHODOLOGY TO ASSESS HDR [superscript]192Ir RADIAL DOSE WITH FRICKE DOSIMETRY
(East Carolina University, 2011)The radial absorbed dose to water, D(r,theta), a quantity not yet directly measured with primary standards, was assessed with the Fricke solution which has been considered as an absolute aqueous solution to perform dosimetry. ... -
Secondary Electron Emission Yields from Fast Fluorine Ions on Copper and Amorphous Solid Water Foils
(East Carolina University, 2011)The biological outcomes from charged particle radiation exposure are heavily influenced by the spatial patterns of energy distributed within the biological system. Monte Carlo track structure codes can be used to model ... -
ANALYTICAL CROSS SECTIONS FOR MOMENTUM TRANSFER TO INNER SHELL ELECTRONS
(East Carolina University, 2011)The Plane Wave Born Approximation (PWBA), the most prevalent First Born Approximation (FBA), serves as input into theories well beyond the scope of the PWBA. Using Mathematica's advanced symbolic programming capabilities ... -
The high concentration of Arg213 → Gly extracellular superoxide dismutase (EC-SOD) in plasma is caused by a reduction of both heparin and collagen affinities
(East Carolina University, 2005-01-15)The C-terminal region of EC-SOD (extracellular superoxide dismutase) mediates the binding to both heparin/heparan sulphate and type I collagen. A mutation (Arg213→Gly; R213G) within this extracellular matrix-binding region ...