Browsing Health Sciences Campus by Title
Now showing items 1089-1108 of 2637
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Hospice nurses' experience of caring for the elderly with wounds at the end-of-life.
(East Carolina University, 2015)Background: The goal of hospice care is to maximize quality of life and provide peace, comfort, and dignity to patients with terminal illness. Older dying patients pose unique challenges to meeting this essential goal, ... -
House Calls at The Country Doctor Museum: Museum Serves Rural Community with Mobile Health Units
(2015-02-06)Symposium poster describes the efforts by The Country Doctor Museum, a small history of rural medicine museum, to meet its community's need for access to health screening and information through the use of mobile health units. -
How Gender Changed the History of Medicine
(2007-04-30)Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ... -
How Sweet It Is: Traditional Sweet Iced Tea and the Diabesity Epidemic.
(2015-01)In this paper we present four cases from our medical practice to increase awareness of the role of sweet tea in obesity and diabetes management. We start with a history of Southern style “sweet tea”, and discuss the ... -
How to cook healthy meals at home on a budget
(2021-02-24)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column discussed how to eat healthy on a budget. -
How to Write a Nutrition-Related Children’s Book with Consideration of Child Perceptions
(East Carolina University, 2018-05-03)This literature review analyzes various peer-reviewed health and psychology journal articles to discover the most effective ways to present information to elementary-aged children in the context of a picture book. Topics ... -
Hox-gene expression as a biomarker for igf-1r therapeutics
(2008-09-25)This invention provides methods for treating or preventing the onset of a tumor in a subject, wherein the tumor is determined to overexpress a Hox gene, including administering to the subject a therapeutically or ... -
The HPV Vaccination Project: HPV Vaccination Following Pediatric Sexual Abuse
(2018-07-17)The nonavalent human papilloma virus (HPV) vaccination prophylactically contributes to the prevention of nine types of HPV associated with vaginal, anal, oropharyngeal, labial, cervical and penile cancers. Rates of HPV ... -
The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP
(2012-07)The homologous cellular coactivators p300 and CBP contain intrinsic lysine acetyl transferase (termed HAT) activity. This activity is responsible for acetylation of several sites on the histones as well as modification of ... -
Human antibodies for immunotherapy development generated via a human B cell hybridoma technology
(East Carolina University, 2006-03-07)Current strategies for the production of therapeutic mAbs include the use of mammalian cell systems to recombinantly produce Abs derived from mice bearing human Ig transgenes, humanization of rodent Abs, or phage ... -
HUMAN RNA METHYLTRANSFERASE METTL16 AFFECTS MULTIPLE CELL PROCESSES THROUGH DIFFERENTIAL FUNCTION OF ITS DOMAINS
(East Carolina University, 2022-11-10)ABSTRACT In recent years, disease therapies have been developed to target specific RNA and protein expression changes in the affected cells/tissue. The RNA post-transcriptional modification, methyl-6-adenosine (m6A), has ... -
Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Protein Interacts with the Cellular Transcription Factor CREB To Inhibit HTLV-1 Transcription
(East Carolina University, 2007-02)The complex human T-cell leukemia virus type 1 (HTLV-1) retrovirus encodes several proteins that are unique to the virus within its 3 -end region. Among them, the viral transactivator Tax and posttranscriptional regulator ... -
Human T-cell Leukemia Virus Type 1 Basic Leucine Zipper Factor (HBZ) Interacts and Inhibits the Acetyltransferase Activity of Multiple Cellular Coactivator Families to Deregulate Transcription
(East Carolina University, 1/13/16)Of the 20 million individuals infected worldwide with the complex retrovirus, Human T-cell Leukemia Virus Type 1, 5% will develop an incurable and fatal form of leukemia known as adult T-cell leukemia (ATL). During the ... -
Human T-Cell Leukemia Virus Type I Basic Leucine Zipper Factor (HBZ) Modulates Cellular DNA Damage Repair and Antioxidant Responses to Promote Host Cell Survival and Leukemogenesis
(East Carolina University, 2018-04-19)Approximately twenty million people worldwide are infected with Human T-cell Leukemia Virus type 1 (HTLV-1). HTLV-1 establishes a life-long, chronic infection which can result in the development of severe HTLV-1 associated ... -
HuR binds to a single site on the C/EBP - beta mRNA of 3T3-L1 Adipocytes
(East Carolina University, 2007-03-30)HuR is a ligand for nuclear mRNAs containing adenylate-uridylate rich elements in the 3'- untranslated region. Once bound to the mRNA, HuR is recognized by adapter proteins which then facilitate nuclear export of the ... -
HuR involvement in mitotic clonal expansion during acquisition of the adipocyte phenotype
(East Carolina University, 2009-05-29)In the nucleus HuR binds to mRNAs containing adenylate-uridylate rich elements in the 3?- untranslated region. HuR may influence expression of its ligand mRNA through regulation of polyadenylation, translocation of the ... -
Hyaluronan Oligosaccharides Inhibit Tumorigenicity of Osteosarcoma Cell Lines MG-63 and LM-8 in Vitro and in Vivo via Perturbation of Hyaluronan-Rich Pericellular Matrix of the Cells
(East Carolina University, 2007-07)Numerous studies have demonstrated a correlation between hyaluronan expression and the malignant properties of various kinds of cancer , and inhibition of hyaluronan production causes decreased tumor growth. Hyaluronan ...