Search
Now showing items 1-10 of 1483
Time course metabolome of Roux-en-Y gastric bypass confirms correlation between leptin, body weight and the microbiome
(2018-05-31)
Roux-en-Y gastric bypass (RYGB) is an effective way to lose weight and reverse type 2 dia- betes. We profiled the metabolome of 18 obese patients (nine euglycemic and nine diabet- ics) that underwent RYGB surgery and seven ...
Is there a metabolic program in the skeletal muscle of obese individuals?
(2011-04-26)
Severe obesity (BMI ≥ 40 kg/m2) is associated with multiple defects in skeletal muscle which contribute to insulin resistance and a reduction in fatty acid oxidation (FAO) in this tissue. These metabolic derangements are ...
OZONE-INDUCED ALTERATIONS IN MACROPHAGE FUNCTION AND THE PROTECTIVE ROLE OF SR-BI
(East Carolina University, 2020-06-22)
Ozone (O3), a criteria air pollutant, is the primary component of photochemical smog. Currently, over 140 million people in the United States are exposed to levels of O3 deemed unhealthy by the Environmental Protection ...
Effects of psychological stressors and [delta]⁹-THC acutely and chronically on zebra finch song behavior and dendritic spine density
(East Carolina University, 2020-06-22)
This dissertation investigated song performance and dendritic spine density, following acute restraint stress in adult zebra finches and, following chronic mild stress and CB1 receptor partial agonist [delta]⁹-tetrahydrocannabinol ...
IMPACT OF INTRINSIC AEROBIC EXERCISE CAPACITY ON CARDIOVASCULAR OUTCOMES FOLLOWING VARIOUS FORMS OF CARDIOVASCULAR STRESS
(East Carolina University, 2020-06-22)
Cardiovascular diseases (CVD) remain the major leading cause of death in the western world. Therefore, several approaches to achieve cardioprotection against any cardiovascular insult have been explored and to date, the ...
Utilizing Metabolomics and Proteomics for Clinical Applications
(East Carolina University, 2020-11-03)
Medical conditions such as heart failure and infant outcomes related to in utero drug exposure have become prevalent amongst the world population. As we observe alarming trends in poor health choices, treating these ...
Acidosis Activated GPR68 Promotes Vascular Smooth Muscle Cell Growth
(East Carolina University, 2020-12-17)
Cardiovascular disease (CVD) is the primary cause of death in the United States and worldwide. Localized extracellular acidosis has been theorized as a possible contributor to CVD pathogenesis, but its precise impact remains ...
Prohibitin: A novel regulator of inflammatory cell dynamics
(East Carolina University, 2020-02-04)
Inflammation is a complex mechanism primarily driven by the immune system to eradicate pathogens/foreign substances and restore tissue homeostasis. Despite the beneficial effects that inflammation employs, signaling can ...
Meeting the Challenge of Providing Nutrition Services During the COVID-19 Pandemic.
(2021-01)
Examples of Registered Dietitian Nutritionists (RDNs) who used their abilities to innovate and adapt to ensure the public, their patients and clients received continuous nutrition services, weight management services, ...
MOTHeRS' Project: Acceptability of a Medically Tailored Food Bag Treating Food Insecurity in High-Risk Pregnant Patients
(2021-08-09)
The MOTHeRS’ Project was developed in 2020 with funding from the United Healthcare Foundation (UHF), ECU Physicians, and the Departments of OB-GYN, Psychiatry and Family Medicine, to utilize NC-STeP—a statewide telepsychiatry ...