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Molecular mechanisms of TMEFF2 action in Prostate Cancer
(East Carolina University, 2013)
The transmembrane protein with epidermal growth factor and two follistatin motifs 2 (TMEFF2) is an evolutionarily conserved type I transmembrane protein expressed in the embryo and limited adult tissues, mainly the brain ...
The involvement of cap-independent mRNA translation in cell fate decisions
(East Carolina University, 2014)
During cell stress many biochemical processes are shut down. For
example, global mRNA translation initiation is inhibited due to the
disruption of the cap-dependent mRNA recruitment mechanism. One
specific example of ...
N-3 polyunsaturated fatty acids differentially enhance B-cell mediated immunity in lean and obese mice
(East Carolina University, 2014)
Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are
bioactive n-3 polyunsaturated fatty acids (PUFAs) in fish oil that
exert immunomodulatory effects. The general paradigm suggests n-3
PUFAs exert immunosuppressive ...