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Now showing items 4621-4640 of 10631
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Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Protein Interacts with the Cellular Transcription Factor CREB To Inhibit HTLV-1 Transcription
(East Carolina University, 2007-02)The complex human T-cell leukemia virus type 1 (HTLV-1) retrovirus encodes several proteins that are unique to the virus within its 3 -end region. Among them, the viral transactivator Tax and posttranscriptional regulator ... -
Human T-cell Leukemia Virus Type 1 Basic Leucine Zipper Factor (HBZ) Interacts and Inhibits the Acetyltransferase Activity of Multiple Cellular Coactivator Families to Deregulate Transcription
(East Carolina University, 1/13/16)Of the 20 million individuals infected worldwide with the complex retrovirus, Human T-cell Leukemia Virus Type 1, 5% will develop an incurable and fatal form of leukemia known as adult T-cell leukemia (ATL). During the ... -
HUMAN T-CELL LEUKEMIA VIRUS TYPE 1-ENCODED PROTEIN HBZ INCREASES VIRAL INFECTION
(East Carolina University, 2017-05-04)Human T-lymphotropic virus type 1 (HTLV-1) is a complex retrovirus, infecting CD4+ T lymphocytes. About 10 million people worldwide are infected with HTLV-1. HTLV-1 has been linked to adult T-cell leukemia (ATL), a disease ... -
Human T-Cell Leukemia Virus Type I Basic Leucine Zipper Factor (HBZ) Modulates Cellular DNA Damage Repair and Antioxidant Responses to Promote Host Cell Survival and Leukemogenesis
(East Carolina University, 2018-04-19)Approximately twenty million people worldwide are infected with Human T-cell Leukemia Virus type 1 (HTLV-1). HTLV-1 establishes a life-long, chronic infection which can result in the development of severe HTLV-1 associated ... -
The Human T-cell Leukemia Virus type I basic leucine zipper factor upregulates the expression of the antioxidant Heme Oxygenase I,
(2019-04-01)Adult T-cell Leukemia/Lymphoma (ATLL) is a resilient lymphoproliferative disease of CD4+ T-cells infected by the Human T-cell Leukemia Virus type I (HTLV-1), for which there are no effective treatments. Mounting evidence ... -
Human Trafficking Awareness
(East Carolina University, 2013)Little research has been conducted concerning public awareness of human trafficking. The purpose of this study was to investigate awareness of human trafficking, including the accuracy and the source of that knowledge. ... -
Human-Animal Bond : Attachment vs. Objectification
(East Carolina University, 2013)The bond between human beings and their pets is multi-faceted. Some doting "parents" view their companion animals as members of their families, while others maintain the more traditional expectation of service or ... -
Human-Environment Interaction and Water Complexities : Mustering Science and Policy for a Coastal Resources Management Approach to Counterinsurgency (COIN) Operations
(East Carolina University, 2012)Managing coastal resources is challenging in the best of circumstances. Bringing science and policy together to manage coastal resources effectively for the purpose of orchestrating population-centric counterinsurgency ... -
Human: An Exploration of the Scientific and Socio-Cultural Factors that Influence What it Means to be Human
(East Carolina University, 2019-05-03)Theatre is a constantly evolving art form. Whereas two hundred years ago plays told the stories of the trials and tribulations of the elite ruling class, today’s shows are moving toward a focus of telling truthful human ... -
Humanitarian aid and its effects on civil conflicts with multiple rebel factions
(East Carolina University, 2019-05-03)Humanitarian aid, protected under the Geneva Convention, is designed to protect four basic measures of human rights, including the right to life, food, basic healthcare, and physical well-being. To meet a basic standard ... -
Hungarian Identity : Constancy and Change in the Father Land, Mother Tongue, and Family Lines
(East Carolina University, 2014)The unique history and language of the Hungarian people have created a distinct cultural identity. Although this unusual identity can be a source of great pride, it also can lead to a sense of isolation and otherness. ... -
HuR binds to a single site on the C/EBP - beta mRNA of 3T3-L1 Adipocytes
(East Carolina University, 2007-03-30)HuR is a ligand for nuclear mRNAs containing adenylate-uridylate rich elements in the 3'- untranslated region. Once bound to the mRNA, HuR is recognized by adapter proteins which then facilitate nuclear export of the ... -
HuR involvement in mitotic clonal expansion during acquisition of the adipocyte phenotype
(East Carolina University, 2009-05-29)In the nucleus HuR binds to mRNAs containing adenylate-uridylate rich elements in the 3?- untranslated region. HuR may influence expression of its ligand mRNA through regulation of polyadenylation, translocation of the ... -
Hurricane Sandy (Panel)
(2013-05-22)Mr. Szatkowski described the experience of Hurricane Sandy from the point of view of forecast meteorologists working in New Jersey area hit by the storm. His office in Mount Holly began issuing warnings forty hours ... -
Hurricane Sandy: Response and Recovery in New York and New Jersey
(2013-05-22)Commander Linda Sturgis is originally from Virginia Beach, Virginia. She began military service in the U.S. Army in 1988 and graduated Old Dominion University in 1992. Shortly after college graduation, she changed ... -
Hurricane Season Forecast 2013
(2013-05-22)Mr. Szatkowski described the 2012 hurricane season. In 2012 there were 19 named storms, 10 reached hurricane strength and 2 were major hurricanes. This exceeded the average number. This year is likely to exceed last year ...