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Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health
(2011-03)The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Integral components of these pathways, Ras, B-Raf, ... -
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: Rationale and importance to inhibiting these pathways in human health
(2011-03-11)The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Integral components of these pathways, Ras, B-Raf, ... -
Rat-bite fever as a cause of septic arthritis: a diagnostic dilemma.
(East Carolina University, 1987-10)Rat-bite fever results from an infection with the organism Streptobacillus moniliformis. Symptomatic patients often present with fever, malaise, cough, maculopapular rash, and occasional arthritis, and usually have a history ... -
A Rationale for the African American Man's Destruction in Alice Walker's Third Life of Grange Copeland and The Color Purple and Zora Neale Hurston's Their Eyes Were Watching God
(East Carolina University, 2012)The African American man is destroyed physically or psychologically in many literary works because he is disliked and/or because of choices he makes. What is intriguing is that African American women writers Zora Neale ... -
Raw beef liver could mean trip to hospital
(2022-08-31)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column involves the medical risks associated with human consumption of raw beef liver. -
RDX and miRNA Expression: Zhang and Pan Respond
(East Carolina University, 2009-03) -
RDX Induces Aberrant Expression of MicroRNAs in Mouse Brain and Liver
(East Carolina University, 2009-02)Background: Although microRNAs (miRNAs) have been found to play an important role in many biological and metabolic processes, their functions in animal response to environmental toxicant exposure are largely unknown. ... -
Re-analyses of “Algal” Genes Suggest a Complex Evolutionary History of Oomycetes
(2017-09-06)The spread of photosynthesis is one of the most important but constantly debated topics in eukaryotic evolution. Various hypotheses have been proposed to explain the plastid distribution in extant eukaryotes. Notably, the ... -
RE-ENGINEERING ATLAS SYSTEMS WITH WATLAS
(East Carolina University, 2021-12-01)The ATLAS language is a legacy language that currently runs on OpenVMS systems. Here, we describe a Windows-based system for re-engineering existing ATLAS applications, transforming them into equivalent C# source code that ... -
Re-evaluation of coastal cultural heritage resources : case study of North Carolina southeastern coastal region
(East Carolina University, 2016-12-15)Humans have had a long history of interconnectedness with the sea and ocean due to the use of natural resources available in the coastal areas. These interactions have influenced the natural landscape and played a crucial ... -
Re-examining the premise of isobaric collisions and a novel method to measure the chiral magnetic effect
(2019-01-22)In these proceedings we show that the premise of the isobaric and collisions to search for the chiral magnetic effect (CME) may not hold as originally anticipated due to large uncertainties in the isobaric nuclear ... -
Re-imaging traditions: Comparison of John Ruskin and Kim Chong-hui
(2003)This research is intended to focus on theories and beliefs of Ruskin and Kim Chong-hui, as they appear in their writings, paintings, and other scholars’ studies on them and to compare these two figures in the historical ... -
RE-IMAGINING PRINCIPAL SUPPORT: A PARTICIPATORY ACTION RESEARCH PROJECT TO ENGAGE PRINCIPALS IN AN EQUITY-CENTERED PROFESSIONAL LEARNING COMMUNITY
(East Carolina University, 2019-12-12)The aim of the PAR project was to engage principals in meaningful professional learning opportunities that supported their growth and development as school and community leaders by participating in an Equity Centered ... -
Reach out and Read: Expanding Child Immunization and Oral Health Literacy Using Quick Response Codes in Pediatric Clinics in North Carolina.
(2022-07-18)Health literacy is essential for positive patient health outcomes. Low literacy among parents, guardians, and patients negatively affects health choices that impact overall health. Reach out and Read (ROR) partners with ... -
Reach Out and Read: Improving Implementation in the Neonatal Intensive Care Unit
(2023-07-23)Infants in the Neonatal Intensive Care Unit (NICU) are at increased risk for neurodevelopmental deficits and delays. Purposeful language exposure, such as reading aloud in the NICU can help offset language delays commonly ... -
Reaching Latino Farmworkers with On-Site Screening for Diabetes and Hypertension
(East Carolina University, 2021-04-23)Background: In the U.S., 29% of Latinos aged 20 or older are diagnosed with hypertension and 12.1% aged 18 or older have diabetes. This increases their risk for other acute and chronic diseases, but their limited healthcare ... -
Reaction to Milk Requires Accurate Diagnosis, Proper Management
(2023-04-26)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column is about the differences between signs/symptoms and treatment of lactose intolerance and cow's milk protein allergy. -
Reactions to a Sexual Assault Disclosure: Evaluation of an Alternative Scoring Method for the Social Reactions Questionnaire
(East Carolina University, 2018-12-10)Survivors of sexual assault receive a wide range of social reactions when they disclose their sexual assault experience to informal support sources (e.g. family and friends). The way in which the survivors perceive these ...