Browsing by Title
Now showing items 9792-9811 of 10629
-
THE π-H ELIX IN FMN-DEPENDENT REDUCTASES PROMOTES OLIGOMERIC CHANGES TO COORDINATE THE MECHANISMS OF THE ALKANESULFONATE MONOOXYGENASE SYSTEMS
(East Carolina University, 2023-08-08)Bacteria two-component flavin-dependent systems are upregulated for sulfur acquisition under sulfur limiting conditions. Two-component flavin-dependent systems are comprised of a reductase (SsuE/MsuE) that catalyzes the ... -
“Their Packaging Has Always Been Like a Power”: A Qualitative Study of U.S. Smokers’ Perceptions of Cigarette Pack Visual Design Features to Inform Product Regulation
(2017-10-17)Cigarette packaging matters to consumer behavior. However, it is less clear which changes to packaging design would be salient for adult smokers. Such information is critically important to regulators in the United States ... -
THEOLOGICAL DISCUSSION AND INSTITUTIONAL CHANGE AT A CHURCH-RELATED INSTITUTION
(East Carolina University, 2012)This study explores the relationship between theological discussion and organizational change within a church-related institution. The qualitative case study examines the dialogue on a campus that received a Lilly Endowment ... -
Theorems in Visual Art: Art and Math Teacher Collaboration toward Creative Leadership
(2018)An artist and a mathematician meet. The authors of this article, one an art education professor and the other a mathematics professor, collaborated to conduct research as a team, examining perceptions of K-12 art ... -
Theoretical aspects and modelling of cellular decision making, cell killing and information-processing in photodynamic therapy of cancer
(2013-09-03)Background: The aim of this report is to provide a mathematical model of the mechanism for making binary fate decisions about cell death or survival, during and after Photodynamic Therapy (PDT) treatment, and to supply the ... -
Theoretical aspects and modelling of cellular decision making, cell killing and information-processing in photodynamic therapy of cancer
(2013)BACKGROUND: The aim of this report is to provide a mathematical model of the mechanism for making binary fate decisions about cell death or survival, during and after Photodynamic Therapy (PDT) treatment, and to supply ... -
Theoretical Probe to the Mechanism of Pt-catalyzed C-H Acylation Reaction: Possible Pathways for the Key Acylation Reaction of Platinacycles
(East Carolina University, 2019-08-23)Transition metal-catalyzed C-H bond functionalization offers a variety of desirable transformations of simple hydrocarbons to more complex compounds with applications being applied in pharmaceuticals to material sciences. ... -
Theoretical studies on the Annexin A1-S100A11 Heterotetramer and Platinum-Mediated C-H Activation Pathways
(East Carolina University, 2023-07-13)Computational chemistry is a powerful tool for characterizing chemical phenomena when they are difficult to observe in laboratory settings or simply elusive. By employing the fundamental equations of nature, computational ... -
THERAPEUTIC AND TOXICOLOGICAL EVALUATION OF BROAD-SPECTRUM ANTIMICROBIAL TRICLOSAN AS A CHEMOTHERAPEUTIC AGENT
(East Carolina University, 2019-05-07)Triclosan (TCS) is a phenolic antimicrobial incorporated in personal care products and medical devices. Interest in the antiproliferative properties of TCS has recently grown owing to its antilipogenic effects. Through the ... -
Therapeutic device to ameliorate stuttering
(East Carolina University, 1999-10-05)A device and method for ameliorating stuttering by providing an altered auditory feedback by employing a compact device configured for positioning in or adjacent the ear canal of an individual. The portable, self-contained ... -
Therapeutic device to ameliorate stuttering
(1999-10-05)A device and method for ameliorating stuttering by providing an altered auditory feedback by employing a compact device configured for positioning in or adjacent the ear canal of an individual. The portable, self-contained ... -
The therapeutic effect of Rho kinase inhibitor Y-27632 on protection from chemotherapy-induced peripheral neuropathy
(2018-04-17)Cisplatin often causes loss of touch sensitivity in the hands and feet of cancer patients as well as tingling, numbness, and a shooting or burning pain; these clinical symptoms are referred to as chemotherapy-induced ... -
The therapeutic effect of Rho kinase inhibitor Y-27632 on protection from chemotherapy-induced peripheral neuropathy
(2018-03-26)Cisplatin often causes loss of touch sensitivity in the hands and feet of cancer patients as well as tingling, numbness, and a shooting or burning pain; these clinical symptoms are referred to as chemotherapy-induced ... -
Therapeutic Intervention: An Initiative to Improve Early Recognition and Response to Patients in Escalating Behavioral Crises
(2023-07-10)Direct care clinical staff on non-mental health units are at risk of abuse, harassment, assault, and disruptive behavior when caring for medical patients with mental or behavioral issues. Early recognition of escalating ... -
The therapeutic potential of Rho GTPase intervention
(East Carolina University, 2013)Small GTPases of the Rho family are well established regulators of critical cellular functions including cytoskeletal remodeling, motility, vesicle trafficking and cell cycle control. Additionally, aberrant signaling ... -
Therapeutic targeting of CK2 in acute and chronic leukemias
(2018-01)Phosphorylation can regulate almost every property of a protein and is involved in all fundamental cellular processes. Thus, proper regulation of phosphorylation events is critical to the homeostatic functions of cell ... -
Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update
(2018-06-26)T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive blood malignancy that arises from the clonal expansion of transformed T-cell precursors. Although T-ALL prognosis has significantly improved due to the development ... -
There Has Never Been Anything Truly Wrong with You
(East Carolina University, 2011)These stories are about obsessive, lonely people. The characters might seem insane but really, they are just lonely and maybe a bit neurotic. They are introspective characters who began life as sweet children, but grew ... -
"There Never Was a Good War or a Bad Peace" : Benjamin Franklin's diplomacy and the 1783 Treaty of Paris
(East Carolina University, 2014)This thesis is an analysis of Benjamin Franklin's actions and motivations as he negotiated the 1783 Treaty of Paris on behalf of the newly created United States. It examines three distinct phases beginning with Franklin's ... -
There’s No Place like Aztlán: The Quest for Queer Homeland through Re-visionism in Chicana Feminist Autohistorias
(East Carolina University, 2019-05-02)In this thesis, I explore how authors Gloria Anzaldúa, Cherríe Moraga, Helena María Viramontes, Ana Castillo, Alicia Gaspar de Alba, Sandra Cisneros, Lorna Dee Cervantes, Carla Trujillo and Felicia Luna Lemus represent ...