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Now showing items 9812-9831 of 10629
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THERE’S TWO SIDES TO EVERY STORY: EXPANDING THE NOMOLOGICAL NETWORK OF BURNOUT THROUGH THE PERSON-ENVIRONMENT INTERACTION
(East Carolina University, 8/5/2020)Burnout is a psychological syndrome consisting of emotional exhaustion, cynicism, and reduced personal accomplishment. It is associated with a depletion of intrinsic resources that results from prolonged exposure to ... -
Thermal stress in artificial cavity-nesting Eastern Bluebirds: killing them with kindness?
(East Carolina University, 2018-05-03)Artificial nest boxes are used to help cavity-nesting species with declining populations that compete for limited nest sites. Proper use of nest boxes has been shown to lower predation rates and ectoparasite loads. However, ... -
Thermodynamic and Spectroscopic Investigations of Novel Antimicrobial Peptides containing Unnatural Amino Acids with Model Membrane Systems
(East Carolina University, 2011)With the over prescription and use of antibiotic drugs the evolution of drug resistant bacteria strains has become a world wide health crisis. In response to this crisis, the search for new drugs to kill bacteria via a ... -
Thermodynamic and spectroscopic studies of Cd²⁺ binding to the regulatory domain and full length human cardiac troponin C (HcTnC) : elucidating plausible Cd²⁺ binding sites
(East Carolina University, 2015)Toxic metals such as cadmium (Cd²⁺) have been shown to bind to and interfere with various calcium (Ca²⁺) binding proteins including the regulatory protein cardiac troponin C (cTnC). Recent structural data has shown that ... -
Thermodynamic and Structural Characterization of Cd(II) binding to human cardiac troponin C: Using Mutants and Truncated Constructs to Elucidate Cd(II) binding sites
(East Carolina University, 8/5/2020)Many biological processes rely on the presence of essential metals; therefore, maintaining the concentration of metals is paramount to homeostasis. Cadmium, Cd(II), is a toxic heavy metal that can disturb this delicate ... -
Thermodynamic Investigation into the Binding Properties of Cardiac Troponin (Human and Bovine)
(East Carolina University, 2010)Troponin is an integral protein in the mechanism of muscle contraction. In order to induce cardiac muscle contraction, Ca[superscript]2[superscript]+ must bind to the TnC subunit (calcium binding subunit) of troponin to ... -
Thermodynamic Investigation of Copper Binding to the Amyloid-Beta (A[beta]) Peptide
(East Carolina University, 2010)Alzheimer's disease is a fatal and neurodegenerative disease with as many as 5.3 million Americans living with the disease. One of the characteristic hallmarks of Alzheimer's is the amyloid plaques that build up around the ... -
Thermodynamic Investigations into Copper Binding in the N-Terminal Region of the Prion Protein at Low Copper Loadings
(East Carolina University, 2010)The prion protein (PrP) is a naturally occurring protein found at high levels in central nervous system (CNS). The misfolding of the PrP is responsible for neurodegenerative diseases called transmissible spongioform ... -
Thermodynamic studies of Ca²⁺ binding to human cardiac troponin C
(East Carolina University, 2012)Human Cardiac Troponin C (HcTnC) is an EF hand protein responsible for initiating contraction of the myocardium (heart muscle). The helix-loop-helix motif, characteristic of members of the EF-hand family, allows HcTnC to ... -
Thesis - generating knowledgebase of common behavior and workflow patterns for secure systems
(East Carolina University, 2018-05-02)Knowledge discovery from large data for system security management and threat detection have been a complex task due to large number of users and the dynamic nature of distributed systems. Healthcare organizations as a ... -
They Really Like Us!: Move From Outputs to Outcomes with Your Library's Research Consultations
(2017-10-18)Learn how librarians at East Carolina took an evidence-based approach to those academic library standbys: one-on-one research consultations. This poster presentation will share our experiences developing a post-meeting ... -
"They Would Have a Law of Their Own" : The Discourse on Smuggling at the Old Bailey, 1736-1814
(East Carolina University, 2013)This thesis examines the cases of 136 men tried for smuggling offenses at London's central criminal court during the long eighteenth century. Before the 1770s, the government portrayed smuggling as a crime against the ... -
They're Speaking Gender Identity, Agency, and Belonging in an International Middle School
(East Carolina University, 2023-04-17)The purpose of the study was to better understand how international school middle school teachers can help cultivate a student's sense of belonging by creating a space for students to explore factors shaping their gender ... -
The Things We Hear in the Nighttime & Other Stories
(East Carolina University, 2015)THE THINGS WE HEAR IN THE NIGHTTIME & OTHER STORIES is a collection of five short stories and five pieces of flash fiction. The writing in the collection focuses on the ever-changing American identity of the 20th and 21st ... -
THINKING MORE DEEPLY & COLLABORATING MORE CLOSELY: HOW CO-TEACHING IS CHANGING STUDENT TEACHING
(East Carolina University, 2021-04-23)Read about the experiences of interns and clinical teachers participating in a co-teaching model of student teaching. Analysis of focus group data from six-years of implementation is shared. Participants will explore the ... -
Thinking Outside of the (Classroom) Box: Collaboration to Enhance Pedagogy
(2012-03-29)RCAW Scholar-Teacher Award -
Thioredoxin Reductase Is Essential for Thiol/Disulfide Redox Control and Oxidative Stress Survival of the Anaerobe Bacteroides fragilis
(East Carolina University, 2007-11)Results of this study showed that the anaerobic, opportunistic pathogen Bacteroides fragilis lacks the glutathione/glutaredoxin redox system and possesses an extensive number of putative thioredoxin (Trx) orthologs. ...