Browsing by Author "Cook, Paul P."
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Cellular miR-150-5p May Have a Crucial Role to Play in the Biology of SARS-CoV-2 Infection by Regulating nsp10 Gene
Akula, Shaw M.; Bolin, Paul; Cook, Paul P. (2022) -
Discontinuation of Transmission Precautions for COVID-19 Patients: Polymerase Chain Reaction Diagnostics, Patient Delays, and Cycle Threshold Values
Burch, Ashley E.; Jiwani, Rahim A.; Mao, Yuxuan; Pona, Adrian; Bradner, Evan; Hussain, Jaffer; Stalls, J. Stephen; Cook, Paul P.; Afriyie, Felix; Labbe, Jonathan; Younes, Ahmed; Badr, Mai; Lee, Elisabeth; Rope, Rachel L. (2021) -
MCF-7 breast cancer cells transfected with protein kinase C-alpha exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype.
Ways, D. Kirk; Kukoly, Cynthia A.; DeVente, James E.; Hooker, Jerry L.; Bryant, Winifred O.; Posekany, Karla J.; Fletcher, Donald J.; Cook, Paul P.; Parker, Peter J. (East Carolina University, 1995-04)Increased protein kinase C (PKC) activity in malignant breast tissue and positive correlations between PKC activity and expression of a more aggressive phenotype in breast cancer cell lines suggest a role for this signal ... -
Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death.
de Vente, James E.; Kukoly, Cynthia A.; Bryant, Winifred O.; Posekany, Karla J.; Chen, Jianming; Fletcher, Donald J.; Parker, Peter J.; Pettit, George J.; Lozano, Guillermina; Cook, Paul P.; Ways, D. Kirk (East Carolina University, 1995-10)Protein kinase C (PKC) modulates growth, differentiation, and apoptosis in a cell-specific fashion. Overexpression of PKC-a in MCF-7 breast cancer cells (MCF-7-PKC-a cell) leads to expression of a more transformed phenotype. ... -
Remote Antimicrobial Stewardship in Community Hospitals
Wood, Zachary H.; Nicolsen, Nicole C.; Allen, Nichole; Cook, Paul P. (2015-11)Antimicrobial stewardship has become standard practice at university medical centers, but the practice is more difficult to implement in remote community hospitals that lack infectious diseases trained practitioners. ... -
Resveratrol Inhibits KSHV Reactivation by Lowering the Levels of Cellular EGR-1
Dyson, Ossie F.; Walker, Lia R.; Whitehouse, Adrian; Cook, Paul P.; Akula, Shaw M. (2012)Article Authors Metrics Comments Related Content Abstract Introduction Results Discussion Materials and Methods Supporting Information Acknowledgments Author Contributions References Reader Comments (0) Media ... -
Resveratrol inhibits KSHV reactivation by lowering the levels of cellular Egr-1
Dyson, Ossie F.; Walker, Lia R.; Whitehouse, Adrian; Cook, Paul P.; Akula, Shaw M. (2012-03-12)In the field of herpesvirus research, the exact molecular mechanism by which such viruses reactivate from latency remains elusive. Kaposi's sarcoma-associated herpesvirus (KSHV) primarily exists in a latent state, while ...