Browsing by Author "Crapo, James D."
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The high concentration of Arg213 → Gly extracellular superoxide dismutase (EC-SOD) in plasma is caused by a reduction of both heparin and collagen affinities
Petersen, Steen V.; Olsen, Dorte Aa.; Kenney, John M.; Oury, Tim D.; Valnickova, Zuzana; Thogersen, Ida B.; Crapo, James D.; Enghild, Jan J. (East Carolina University, 2005-01-15)The C-terminal region of EC-SOD (extracellular superoxide dismutase) mediates the binding to both heparin/heparan sulphate and type I collagen. A mutation (Arg213→Gly; R213G) within this extracellular matrix-binding region ...