Browsing by Author "Freistaedter, Andrew"
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Development of improved therapeutic mesothelin-based vaccines for pancreatic cancer
White, Michael; Freistaedter, Andrew; Jones, Gwendolyn J B; Zervos, Emmanuel; Roper, Rachel L (2018-02-23)Pancreatic cancer is the 5th leading cause of cancer deaths, and there are no effective treatments. We developed a poxvirus platform vaccine with improved immunogenicity and inserted the mesothelin gene to create an ... -
Murine mesothelin: characterization, expression, and inhibition of tumor growth in a murine model of pancreatic cancer
Zervos, Emmanuel; Agle, Steven C.; Freistaedter, Andrew; Jones, Gwendolyn; Roper, Rachel (2016)Background: Mesothelin has attracted much interest as a tumor specific antigen; it has been reported to promote tumor development and to be a good target for cancer treatment. Most studies to date have used human mesothelin ...