Browsing by Author "Leonard, Sherry Ann"
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Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance.
Nyce, Jonathan W.; Leonard, Sherry Ann; Canupp, Dawn; Schulz, Stefan; Wong, So (East Carolina University, 1993-04-01)In a model system employing Chinese hamster V-79 cells, the DNA synthesis inhibitor 3'-azido-3'- deoxythymidine (BW A509U, AZT) was shown to induce genome-wide DNA hypermethylation, low-frequency silencing of thymidine ... -
Neuropeptide Y analogues, compositions and methods of lowering blood pressure
Nyce, Jonathan W.; Leonard, Sherry Ann (2000-06-13)Neuropeptide Y analogues, and their compositions are effective for lower blood pressure.