Oncology
Permanent URI for this collectionhttp://hdl.handle.net/10342/96
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Item Open Access Management of Venous Thromboembolism in High-Grade Glioma: Does Low Molecular Weight Heparin Increase Intracranial Bleeding Risk?(2022) Jo, Jasmin; Donahue, Joseph; Sarai, Guneet; Petroni, Gina; Schiff, DavidItem Open Access Surveillance Imaging Frequency in Adult Patients with Lower-Grade (WHO Grade 2 and 3) Gliomas(2022-02-08) Jo, Jasmin; et alItem Open Access Impact of Older Age in Patients Receiving Atezolizumab and Bevacizumab for Hepatocellular Carcinoma(2022) Amar, Suneetha; Muzaffar, Mahvish; Naqash, Abdul Rafeh; Vithayathil, Mathew; et alItem Open Access A Soft Spot(2022-03-17) Snyder, Rebecca A.Item Open Access A 3D Star Shot to Determine the Gantry, Collimator, and Couch Axes Positions(2022) Corns, Robert; Yang, Kaida; Ross, Mason; Bhandari, Shiva; Aryal, Makunda; Ciaccio, PeterItem Open Access Item Open Access Patterns and Outcomes of Subsequent Therapy After Immune Checkpoint Inhibitor Discontinuation in HCC(2022) Muzaffar, Mahvish; Bulumulle, Anushi; Sharma, RohiniItem Open Access Non-invasive Cancer Detection in Canine Urine Through Caenorhabditis Elegans Chemotaxis(2022-08-09) Lee, Myon Hee; Namgong, ChanItem Open Access Survival Is Worse in Patients Completing Immunotherapy Prior to SBRT/SRS Compared to Those Receiving It Concurrently or After(2022-05-27) Woody, Susan; Hegde, Aparna; Arastu, Hyder; Peach, M. Sean; Ju, Andrew W.; Sharma, Nitika; Walker, PaulItem Open Access Volume of Disease as a Predictor for Clinical Outcomes in Patients With Melanoma Brain Metastases Treated With Stereotactic Radiosurgery and Immune Checkpoint Therapy(2022-01-12) Burke, Aidan M.; Carrasquilla, MichaelItem Open Access The Systemic Inflammatory Response Identifies Patients with Adverse Clinical Outcome from Immunotherapy in Hepatocellular Carcinoma(2022) Muzaffar, Mahvish; Navaid, Musharraf; Naqash, Abdul RafehItem Open Access The Impact of Curated Educational Videos on Pathology Health Literacy for Patients with a Pancreatic, Colorectal, or Prostate Cancer Diagnosis(2022) Khanchandani, Ashish T.; Larkins, Michael C.; Tooley, Ann M.; Meyer, David B.; Chaudhary, Vijay; Fallon, John T.Item Open Access Association of Extended Dosing Intervals or Delays in Pembrolizumab-Based Regimens With Survival Outcomes in Advanced Non-small-cell Lung Cancer(2021) Bulumulle, Anushi; Brody, Heather; Macherla, Shravanti; Walker, Paul R.; Sehgal, Kartik; Gill, Ritu R.; Qilleri, Aleksandra; McDonald, Danielle C.; Cherry, Cynthia R.; Shea, Meghan; Huberman, Mark S.; VanderLaan, Paul A.; Weiss, Glen J.; Costa, Daniel B.; Rangachari, DeepaItem Open Access Early Antibiotic Exposure Is Not Detrimental to Therapeutic Effect from Immunotherapy in Hepatocellular Carcinoma(2021-10-08) Muzaffar, Mahvish; Navaid, Musharraf; Bulumulle, Anushi; Fessas, Petros; Naeem, Muntaha; Pinter, Matthias; Marron, Thomas U.; Szafron, DavidItem Open Access Early Antibiotic Exposure Is Not Detrimental to Therapeutic Effect from Immunotherapy in Hepatocellular Carcinoma(2021-10-08) Muzaffar, Mahvish; Navaid, Musharraf; Bulumulle, Anushi; Fessas, Petros; Naeem, Muntaha; Pinterb, Matthias; Marron, Thomas U.; Szafron, David; Balcar, Lorenz; Saeed, Anwaar; Jun, Tomi; Dharmapuri, Sirish; Gampa, Anuhya; Wang, Yinghong; Khan, Uqba; Lee, Pei-Chang; Yu, Bo; Paul, Sonal; Nimkar, Neil; Bettinger, Dominik; Hildebrand, Hannah; Abugabal, Yehia I.; Pressiani, Tiziana; Personeni, Nicola; Nishida, Naoshi; Kudo, Masatoshi; Kaseb, Ahmed; Huang, Yi-Hsiang; Ang, Celina; Pillai, Anjana; Rimassa, Lorenza; Naqash, Abdul Rafeh; Sharon, Elad; Cortellini, Alessio; Pinato, David J.Item Open Access Pancreatic Cancer Incidence Trends in the United States from 2000-2017: Analysis of Surveillance, Epidemiology and End Results (SEER) Database(2021) Ali, Hassam; Pamarthy, Rahul; Vallabhaneni, Meghana; Sarfraz, Shiza; Ali, Hadiqa; Rafique, HamzaItem Open Access Method of detecting cancer using delta-catenin(2008-11-04) Lu, Qun; Chen, Yan-HuaThe present invention provides a method for detecting or screening for the presence of cancer in a subject. The method comprises obtaining, providing or collecting a tissue or fluid sample (such as a urine sample) from said subject, and then determining the presence or absence of delta-catenin in said sample, or increased levels of delta-catenin in said sample as compared to a normal or control subject. The presence of delta-catentin in said sample, or increased levels of delta-catenin in said sample, indicating said subject is afflicted with or at least at risk of developing cancer.Item Open Access Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors(2016-09-21) Guo, Lu; Wang, Gang; Feng, Yuanming; Yu, Tonggang; Guo, Yu; Bai, Xu; Ye, ZhaoxiangAbstract Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they are able to detect tumor volume and physiological changes beyond the lesions shown on conventional MRI. This review examines recent studies that utilized diffusion and perfusion MRI for tumor volume definition in radiotherapy of brain tumors, and it presents the opportunities and challenges in the integration of multimodal functional MRI into clinical practice. The results indicate that specialized and robust post-processing algorithms and tools are needed for the precise alignment of targets on the images, and comprehensive validations with more clinical data are important for the improvement of the correlation between histopathologic results and MRI parameter images.Item Open Access On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study(2010) Li, Taoran; Zhu, Xiaofeng; Thongphiew, Danthai; Lee, W. Robert; Vujaskovic, Zeljko; Wu, Qiuwen; Yin, Fang-Fang; Wu, Q. JackieThe purpose of this paper is to evaluate the feasibility and clinical dosimetric benefit of an on-line, that is, with the patient in the treatment position, Adaptive Radiation Therapy (ART) system for prostate cancer treatment based on daily cone-beam CT imaging and fast volumetric reoptimization of treatment plans. A fast intensity-modulated radiotherapy (IMRT) plan reoptimization algorithm is implemented and evaluated with clinical cases. The quality of these adapted plans is compared to the corresponding new plans generated by an experienced planner using a commercial treatment planning system and also evaluated by an in-house developed tool estimating achievable dose-volume histograms (DVHs) based on a database of existing treatment plans. In addition, a clinical implementation scheme for ART is designed and evaluated using clinical cases for its dosimetric qualities and efficiency.Item Open Access Feasibility of image-guided radiotherapy based on helical tomotherapy to reduce contralateral parotid dose in head and neck cancer(2012) Nguyen, Nam P.; Vos, Paul; Vinh-Hung, Vincent; Ceizyk, Misty; Smith-Raymond, Lexie; Stevie, Michelle; Slane, Benjamin; Chi, Alexander; Desai, Anand; Krafft, Shane P.; Jang, Siyoung; Hamilton, Russ; Karlsson, Ulf; Abraham, DaveBackground To evaluate the feasibility of image-guided radiotherapy based on helical Tomotherapy to spare the contralateral parotid gland in head and neck cancer patients with unilateral or no neck node metastases. Methods A retrospective review of 52 patients undergoing radiotherapy for head and neck cancers with image guidance based on daily megavoltage CT imaging with helical tomotherapy was performed. Results Mean contralateral parotid dose and the volume of the contralateral parotid receiving 40 Gy or more were compared between radiotherapy plans with significant constraint (SC) of less than 20 Gy on parotid dose (23 patients) and the conventional constraint (CC) of 26 Gy (29 patients). All patients had PTV coverage of at least 95% to the contralateral elective neck nodes. Mean contralateral parotid dose was, respectively, 14.1 Gy and 24.7 Gy for the SC and CC plans (p < 0.0001). The volume of contralateral parotid receiving 40 Gy or more was respectively 5.3% and 18.2% (p < 0.0001) Conclusion Tomotherapy for head and neck cancer minimized radiotherapy dose to the contralateral parotid gland in patients undergoing elective node irradiation without sacrificing target coverage.
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