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The genomes of two key bumblebee species with primitive eusocial organization
(2015-04-24)
Background
The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. ...
High major histocompatibility complex class I polymorphism despite bottlenecks in wild and domesticated populations of the zebra finch (Taeniopygia guttata)
(2015-12-01)
Background
Two subspecies of zebra finch, Taeniopygia guttata castanotis and T. g. guttata are native to Australia and the Lesser Sunda Islands, respectively. The Australian subspecies has been domesticated and is now an ...
A non-tight junction function of claudin-7—Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment
(2015-06-17)
Background
Claudins are a family of tight junction (TJ) membrane proteins involved in a broad spectrum of human diseases including cancer. Claudin-7 is a unique TJ membrane protein in that it has a strong basolateral ...
Short-term, high-fat diet accelerates disuse atrophy and protein degradation in a muscle-specific manner in mice
(2015-11-04)
Background:
A short-term high-fat diet impairs mitochondrial function and the ability of skeletal muscle to respond to growth stimuli, but it is unknown whether such a diet alters the ability to respond to atrophy signals. ...
Influence of exercise mode on pregnancy outcomes: ENHANCED by Mom project
(2015-06-09)
Background:
The extent of the benefits of exercise training during pregnancy on maternal, fetal, and neonatal health outcomes has not been sufficiently addressed. While aerobic exercise training has been determined as ...
PI3K mediated activation of GSK‑3β reduces at‑level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias
(2015-06-21)
Background
Neuropathic pain and sensory abnormalities are a debilitating secondary consequence of spinal cord injury (SCI). Maladaptive structural plasticity is gaining recognition for its role in contributing to the ...
EHR and Cost: Is "Meaningful Use" Meaningfully Reducing Health Care Costs?
(2015)
The United States of America is one of the top spenders on health care per capita in the world; in 2013, we spent twice as much as France, a country known for having quality health care for its citizens (OECD, 2013). As a ...
Lexical diversity in Parkinson’s disease
(2015-03-02)
Background: Parkinson’s disease (PD) is a neurodegenerative syndrome of the basal ganglia (BG) believed to disrupt cortical-subcortical pathways critical to motor, cognitive and expressive language function. Recent studies ...
Auditory and visual sustained attention on tasks with varied motivation and cognitive loads in children with and without ADHD.
(East Carolina University, 2015)
Attention Deficit Hyperactivity Disorder (ADHD) is a common condition that can make tasks difficult for the children affected, particularly in a school environment. Continuous performance tasks are one means of evaluating ...
Auditory brainstem responses to air- and bone-conducted chirp stimuli in newborns and young adults.
(East Carolina University, 2015)
Over the past half a century, considerable effort has been dedicated to the development of universal newborn hearing screening (UNHS) programs across the United States. Newborn hearing screenings have progressed from ...