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A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction
(East Carolina University, 2008-11-01)
Mutations in COCH (coagulation factor C homology) are etiologic for the late-onset, progressive, sensorineural hearing loss and vestibular dysfunction known as DFNA9. We introduced the G88E mutation by gene targeting into ...
Systemic Nutrition: What's YOUR Gut Reaction?
(East Carolina University, 2008)
Presentation accompanying lecture for receiving the Lenna Frances Cooper Award at the 2008 Food and Nutrition Conference and Exhibition of the American Dietetic Association
Otoconin-90 Deletion Leads to Imbalance but Normal Hearing: A Comparison with Other Otoconia Mutants
(East Carolina University, 2008-04)
Our sense of gravitation and linear acceleration is mediated by stimulation of vestibular hair cells through displacement of otoconia in the utricle and saccule (the gravity receptor organ). We recently showed that otoconin-90 ...
Utilization of Information Technology in Eastern North Carolina Physician Practices: Determining the Existence of a Digital Divide
(East Carolina University, 2008)
The United States Department of Health and Human Services (DHHS) has emphasized the importance of utilizing health information technologies, thus making the availability of electronic resources critical for physicians ...
Using Wiki in an Online Record Documentation Systems Course
(East Carolina University, 2008-01-30)
We report a case study using a wiki tool, Confluence, including a brief history, current status, and motivations for using Confluence. We describe how we created two spaces on Confluence for two consecutive classes, 2006 ...
Resting Discharge Patterns of Macular Primary Afferents in Otoconia-Deficient Mice
(East Carolina University, 2008-12)
Vestibular primary afferents in the normal mammal are spontaneously active. The consensus hypothesis states that such discharge patterns are independent of stimulation and depend instead on excitation by vestibular hair ...
Osteopontin is not Critical for Otoconia Formation or Balance Function
(East Carolina University, 2008-06)
Unlike the structural and mechanical role of bone crystals, the inertial mass of otoconia crystals provides a shearing force to stimulate the mechanoreceptors of the utricle and saccule (the gravity receptor organ)under ...
Priming Anxiety into People who Stutter: Arousal's Influence on Fluency
(East Carolina University, 2008-11)
Many experimental psychologists (Bargh, Chen & Burrows, 1996; Berner & Maier, 2004; Bowers, 1999; Chartrand, VanBaaren & Bargh, 2006; Chen & Haviland-Jones, 2000; Hazlett, Dawson, Schell & Filion, 1990; Macky-Sim & Laing, ...