RSS 1.0Master's Theses
Recent Submissions
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Mutations to ettA and lepA Cause Acinetobacter baumannii to Overcome Growth Defects in the DcsrA Strain in the Presence of Amino Acids
(East Carolina University, 2023-07-10)Acinetobacter baumannii is a Gram-negative bacterial pathogen which often causes nosocomial infections. A. baumannii is known for its incredible ability to survive drying and its high rates of multidrug resistance. Carbapenem ... -
Computational Modeling of Arteriovenous Fistula Hemodynamics in Pulmonary Hypertension Patients
(East Carolina University, 2023-07-21)In the United States, approximately 50 million people suffer from chronic kidney disease, which over time progresses to end-stage renal disease (ESRD). Care for these patients is typically managed by dialysis with the ... -
Impacts of environmentally relevant levels of the perfluorooctanoic acid (PFOA) replacement compound GenX (Hexafluoropropylene Oxide Dimer Acid) on feeding behavior, mitochondrial ROS, and gene expression in Caenorhabditis elegans
(East Carolina University, 2023-08-03)Per- and polyfluoroalkyl substances (PFAS) are commercially manufactured chemicals known for widespread usage in different industries. Past research indicating negative health impacts and bioaccumulation in humans and the ... -
A Comparative Study on MFCC, GFCC, BFCC, and CQCC Spectral Speech Feature Performance in X-Vector Clustering
(East Carolina University, 2023-07-25)Speaker diarization plays a crucial role in accurately identifying speakers in audio or video streams with multiple speakers. However, the use of Mel-frequency cepstral coefficients (MFCC) as the default speaker feature ... -
Investigations of the Brevard Fault zone and Tugaloo Terrane adjacent to the Grandfather Mountain Window, North Carolina
(East Carolina University, 2023-07-24)The Brevard Fault Zone adjacent to the Grandfather Mountain window, NC is interpreted to be a terrane boundary between Laurentian margin rocks and accreted rocks of the Tugaloo Terrane. Structural, geochemical, and ... -
PAH Contamination Variability in the Lower Tar River N.C. From a Legacy Hazardous Waste Site as a Function of Hydrological Conditions
(East Carolina University, 2023-08-18)Polycyclic aromatic hydrocarbons (PAHs) are a class of trace organic contaminants that can enter the environment from both natural and anthropogenic sources. Of these compounds, 16 are listed as high-priority contaminants ... -
USING ENVIRONMENTAL DNA (eDNA) TO MONITOR RIVER HERRING MOVEMENT WITHIN A COASTAL NORTH CAROLINA WATERSHED
(East Carolina University, 2023-08-09)Blueback Herring (Alosa aestivalis) and Alewife (A. pseudoharengus) are two threatened species in the genus Alosa that use eastern North Carolina's coastal rivers and estuaries to spawn. In North Carolina watersheds, river ... -
Characterization of rat models of type two diabetes and metabolic syndrome and the evaluation of SDF-1 mRNA as a treatment for erectile dysfunction
(East Carolina University, 2023-07-24)Erectile Dysfunction (ED) affects a considerable population of men and can have a profound negative impact on their quality of life and well-being. ED is often a consequence of age and diseases that affect the microvasculature ... -
SOCIAL REGULATION OF THE A11 DOPAMINERGIC NUCLEUS IN ZEBRAFISH (_Danio rerio_)
(East Carolina University, 2023-07-17)Aggression is a universal behavioral feature that is present in majority of social animals. In nature, aggression facilities the formation and stabilization of social relationships and allow animals to divide resources ... -
Myocardial Implications in Renin Angiotensin Aldosterone-Regulated Hypertension
(East Carolina University, 2023-08-08)Hypertension is a prevalent and potentially deadly disease that affects approximately 116 million (47%) adults diagnosed in the U.S. as reported by the CDC in 2017. Understanding mechanisms responsible for high blood ... -
eHEALTH LITERACY, MEDICAL MISTRUST AND CERVICAL CANCER PREVENTION KNOWLEDGE, BELIEFS AND BEHAVIORS AMONG AFRICAN AMERICAN WOMEN
(East Carolina University, 2023-07-17)Cervical cancer (CC) is a major global public health problem and is the third most common cancer among women worldwide. In the United States, African Americans have the second highest incidence rates of CC, due to having ... -
Determination of the Role of Tyrosine-319 on the Efficiency of Photoinduced Radical Pairs in Avian Cryptochrome Photoreceptor Proteins Related to Magnetoreception
(East Carolina University, 2023-07-17)Cryptochromes (CRYs) are flavin-containing blue light photoreceptors which are involved in circadian rhythms and magnetoreception. CRYs are structurally related to DNA photolyases. While photolyases use light-driven FAD ... -
ASSOCIATION BETWEEN CUMULATIVE LIFETIME STRESS, COGNITIVE FUNCTION AND SLEEP: THE MODERATING EFFECTS OF RESILIENCE
(East Carolina University, 2023-07-21)Stress is multidimensional and can be labeled as acute, chronic, or cumulative. Cumulative lifetime stress encompasses the exposure to stressors occurring over the course of the lifetime, instead of focusing on a specific ... -
Covalent Conjugation of 2-Hydroxyethylmethacrylate with an Anti-Biofouling 2-Aminoimidazole Small Molecule and its Effect on an Experimental Dental Adhesive
(East Carolina University, 2023-06-22)Secondary caries, or cavities that have re-infected previously restored teeth, are a prevalent problem in the oral health community. An overwhelming 74% of restored teeth require further work and replacement restorations; ... -
MICROBIAL INFLUENCED CORROSION ON ACCOMAC, A FRESHWATER, FERROUS-HULLED SHIPWRECK: EVALUATION OF MICROBIAL DIVERSITY AND COMPOSITION
(East Carolina University, 2023-07-09)Abandoned shipwrecks are sitting at the bottom of oceans and lakes around the world, deteriorating extensively as the years pass by. Over time, however, microbial-comprised biofilm formation on these structures has resulted ... -
Social and Emotional Impact of Group Engagement in Occupations Among Cancer Survivors
(East Carolina University, 2023-07-21)Rationale: Due to medical and technological advancements, the cancer death rate has declined significantly in recent years, leading to an increase in the number of cancer survivors. A cancer diagnosis impacts an individual’s ... -
Evidence for an association between genetic and acoustic variation in a poison frog
(East Carolina University, 2023-07-21)Acoustic signaling is a key component in both intra- and inter-specific interactions. These signals can be used in many contexts, including mating behavior and agonistic interactions. Poison frogs are of particular interest ... -
Understanding the Impact of a Low-Commitment Scientific Innovation Modules on Undergraduate Biology Students’ Grit, Retention, Biology Interest, and Biology Self-Efficacy
(East Carolina University, 2023-07-21)Introducing innovation courses to engineering and computer science has been shown to increase retention and interest in the discipline. These courses have generally been high commitment, in that they take place over an ... -
JUST THROW STRIKES! THE RELATIONSHIP BETWEEN QUIET EYE DURATION AND BASEBALL PITCHING ACCURACY IN LOW- AND HIGH-PRESSURE TASKS
(East Carolina University, 2023-08-07)For athletes to achieve high-performance levels in sport, precise control of attention and physical action is essential to provide the movement planning systems with adequate information to execute the appropriate movement ... -
Theoretical studies on the Annexin A1-S100A11 Heterotetramer and Platinum-Mediated C-H Activation Pathways
(East Carolina University, 2023-07-13)Computational chemistry is a powerful tool for characterizing chemical phenomena when they are difficult to observe in laboratory settings or simply elusive. By employing the fundamental equations of nature, computational ...