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Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood
(2016)
Background: Insulin, a pleotrophic hormone, has diverse effects in the body. Recent work has highlighted the important role of insulin's action in the nervous system on glucose and energy homeostasis, memory, and mood. ...
Mitochondrial Diagnostics: A Multiplexed Assay Platform for Comprehensive Assessment of Mitochondrial Energy Fluxes
(2018-09-25)
Chronic metabolic diseases have been linked to molecular signatures of mitochondrial dysfunction. Nonetheless, molecular remodeling of the transcriptome, proteome, and/or metabolome does not necessarily translate to ...
A case of Exophiala oligosperma successfully treated with voriconazole
(2013-08-30)
Exophiala oligosperma is an uncommon pathogen associated with human infections, predominantly in immunocompromised hosts. Case reports of clinical infections related to E. oligosperma have been limited to 6 prior publications, ...
Serum metabolomic profiling in acute alcoholic hepatitis identifies multiple dysregulated pathways
(2014-12-02)
Background and Objectives While animal studies have implicated derangements of global energy homeostasis in the pathogenesis of acute alcoholic hepatitis (AAH), the relevance of these findings to the development of human ...
A Method for Detecting Positive Growth Autocorrelation without Marking Individuals
(2013-10-28)
In most ecological studies, within-group variation is a nuisance that obscures patterns of interest and reduces statistical power. However, patterns of within-group variability often contain information about ecological ...
Species-specific expansion and molecular evolution of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) gene family in plants
(2014-04-10)
The terpene compounds represent the largest and most diverse class of plant secondary metabolites which are important in plant growth and development. The 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR; EC 1.1.1.34) ...
Changes in zooplankton community, and seston and zooplankton fatty acid profiles at the freshwater/saltwater interface of the Chowan River, North Carolina
(2017-08-16)
The variability in zooplankton fatty acid composition may be an indicator of larval fish habitat quality as fatty acids are linked to fish larval growth and survival. We sampled an anadromous fish nursery, the Chowan River, ...
Influence of Community‐Based Dental Education on Practice Choice: Preliminary Data from East Carolina University
(2019-09-01)
Maldistribution of the dental workforce contributes to poor access to oral health care. Community‐based dental education (CBDE) may help to address this problem by using experiential learning to encourage new dentists to ...
Where SNAC Fits: SNAC in the Workflow at Joyner Library
(2019)
Overview of the integration of archival authority records via SNAC into the workflow at East Carolina University's J.Y. Joyner Library.