Browsing College of Health and Human Performance by Subject "Obesity"
Now showing items 1-20 of 31
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ASSESSMENT OF HOW INTERNALIZED FORMS OF MOTIVATION MEDIATE THE RELATIONSHIP BETWEEN SUPPORTS FOR BASIC PSYCHOLOGICAL NEEDS AND PHYSICAL ACTIVITY BEHAVIORS
(East Carolina University, 2013)The prevalence of obesity has increased steadily over the last 30 years and it is a growing concern for school, health and recreation providers. Decreases in time spent in physical activity and increased participation in ... -
EFFECT OF A TELEPHONE-BASED INTERVENTION ON PHYSICAL ACTIVITY AND COMPONENTS OF THE METABOLIC SYNDROME IN ADOLESCENTS
(East Carolina University, 2013)The purpose of this study was to determine the effects of a two month telephone-based intervention in obese adolescents (BMI percentile [greater than or equal to] 95th percentile) on physical activity habits and motivation ... -
Effect of Acute Exercise or Fasting on Mitochondrial Function and High Fat Diet-Induced Insulin Resistance
(East Carolina University, 2009)A high-fat diet leads to an accumulation of lipid in skeletal muscle, and the development of both mitochondrial dysfunction and insulin resistance. Recently, our lab reported that lipid overload leads to elevated ... -
THE EFFECT OF CONTRACTILE ACTIVITY AND SUBSTRATE CHALLENGES ON METABOLIC FLEXIBILITY IN HUMAN PRIMARY MYOTUBES
(East Carolina University, 2013)The skeletal muscle of severely obese individuals (BMI > 40 kg/m²) is characterized by a depressed ability to oxidize fatty acids and a failure to upregulate fatty acid oxidation (FAO) in response to increased lipid ... -
Effect of exercise intensity and volume on persistence of insulin sensitivity during training cessation
(East Carolina University, 2009-04)Effect of exercise intensity and volume on persistence of insulin sensitivity during training cessation. J Appl Physiol 106: 1079â 1085, 2009. First published February 5, 2009; doi:10.1152/japplphysiol.91262.2008. The ... -
Effects of High-Insulin Exposure on Mitochondrial Content in Skeletal Muscle Myotubes from Lean & Severely Obese Individuals: A Time Course Analysis
(East Carolina University, 2016-08-01)Skeletal muscle is the site at which highly regulated energetic processes take place as a means of maintaining both tissue-specific and whole-body metabolism. With the development of severe obesity (BMI [greater-than] or ... -
EFFECTS OF MODERATE AEROBIC EXERCISE ON THE ATTENUATION OF LEAN MASS LOSS DURING RAPID WEIGHT LOSS
(East Carolina University, 2013)Background: Obesity has become a severe issue in the United States, and gastric bypass surgery has been one of the most successful tools to combat the adverse consequences of this disease. The rapid weight loss associated ... -
Effects of obesity on the transcriptional regulation of protein degradation in skeletal muscle
(East Carolina University, 2013)Effects of obesity on the transcriptional regulation of protein degradation in skeletal muscle by Lance M. Bollinger November, 2013 Director of Thesis/Dissertation: Jeffrey J. Brault Major Department: Kinesiology ... -
Effects of Parental Obesity on Fat Metabolism During Submaximal Exercise in Children
(East Carolina University, 2009)The aim of the present study was to compare fat metabolism during submaximal exercise in children with a morbidly obese parent - (COP) (BMI [greater than or equal to] 40 kg/m²) to children with relatively lean parents - ... -
High-Fat Diet Induced Obesity Increases Serum Myostatin, but Does Not Accelerate Skeletal Muscle Atrophy
(East Carolina University, 2013)Myostatin is a potent negative regulator of muscle mass, i.e. high levels of myostatin induce loss of muscle. Surprisingly, severely obese humans and obese mice have elevated levels of serum myostatin, but the role of ... -
IL-15 : A NOVEL REGULATOR OF LIPOLYSIS IN HUMANS?
(East Carolina University, 2014)Interactions between and within organ systems such as skeletal muscle (SkM) and adipose tissue (AT), via immune cell signaling factors (cytokines), may regulate the development of obesity. The increased expression and ... -
Increased Secretion and Expression of Myostatin in Skeletal Muscle From Extremely Obese Women
(East Carolina University, 2009-01)OBJECTIVE- Obesity is associated with endocrine abnormalities that predict the progression of insulin resistance to type 2 diabetes. Because skeletal muscle has been shown to secrete proteins that could be used as biomarkers, ... -
The Influence of BMI and Self-Efficacy Levels on the Accuracy in Self-Reported Physical Activity Recall
(East Carolina University, 2011)The purpose of this study was to compare self-reported and objectively measured physical activity levels among college students with different body mass index (BMI) classifications (normal weight and overweight/obese), in ... -
The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale
(East Carolina University, 2009-07-28)Background: Obesity is the most modifiable risk factor, and dietary induced weight loss potentially the best nonpharmacologic intervention to prevent or to slow osteoarthritis (OA) disease progression. We are currently ... -
Intramuscular Lipid Metabolism, Insulin Action and Obesity
(East Carolina University, 2009-01)With the increasing prevalence of obesity, research has focused on the molecular mechanism(s) linking obesity and skeletal muscle insulin resistance. Metabolic alterations within muscle, such as changes in the cellular ... -
The lived experience of obese employees who discontinued voluntary participation in a workplace weight loss challenge program : A qualitative study
(East Carolina University, 2014)This phenomenological qualitative study, guided by Max van Manen, addressed the question, "What is the lived experience of obese employees who discontinued participation in a workplace weight loss challenge program in which ... -
Metabolic Inflexibility in Response to Lipid Oversupply with Obesity: Epigenetic Modifications Play a Role
(East Carolina University, 2013)The ability to adjust substrate oxidation according to nutrient availability has been termed `metabolic flexibility' and is a critical factor in overall metabolic health. In respect to fatty acid oxidation (FAO) metabolic ... -
Mitochondrial Oxidative Capacity In Human Skeletal Muscle: Association with Plasma Lactate Concentration
(East Carolina University, 2018-07-11)ABSTRACT Background: Metabolic disease is a growing concern for public health. Obesity and Type II Diabetes are an epidemic and a phenotype for insulin resistance in human skeletal muscle. A reduced mitochondrial function ... -
NADPH Oxidase as a Mechanistic Link Between Erectile Dysfunction, Peripheral, and Coronary Endothelial Dysfunction in Obesity
(East Carolina University, 2012)Cardiovascular complications involving both microvascular and macrovascular tissues are the major cause of morbidity and mortality in obese patients. Clinical and epidemiological studies suggest that erectile dysfunction ...