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Relative fat oxidation is higher in children than adults
(East Carolina University, 2007-08-16)
Background: Prepubescent children may oxidize fatty acids more readily than adults. Therefore, dietary fat needs would be higher for children compared with adults. The dietary fat recommendations are higher for children 4 ...
A Comparison of Lean and Obese Gait Characteristics of Children and Adults During Level Walking
(East Carolina University, 2010)
Increased body mass affects gait kinematics and kinetics in adults. It is however unknown if increased body mass produces similar adaptations in children and adults. The duration of obesity in children is shorter than ...
A single dose of metformin improves whole body insulin sensitivity and alters cellular redox state in skeletal muscle of Zucker fa/fa rats
(East Carolina University, 2010)
Energy balance is considered a fundamental requirement of life forms from single cell organisms to higher mammals such as humans. Unfortunately, our species has also discovered the detrimental metabolic responses to excess ...
Intramuscular Lipid Metabolism, Insulin Action and Obesity
(East Carolina University, 2009-01)
With the increasing prevalence of obesity, research has focused on the molecular mechanism(s) linking obesity and skeletal muscle insulin resistance. Metabolic alterations within muscle, such as changes in the cellular ...
STRIDE LENGTH MANIPULATION IN YOUNG AND OLD ADULTS DURING LEVEL WALKING
(East Carolina University, 2010)
Physiological and neurological changes with healthy aging cause old adults to alter biomechanical gait strategies. Mechanical plasticity is an ambulatory strategy in which old adults rely on proximal musculature in ...
FATE AND TRANSPORT OF WASTEWATER PHOSPHORUS IN THE NORTH CAROLINA COASTAL PLAIN : A COMPARISON OF WATERSHEDS SERVED BY MUNICIPAL AND ONSITE WASTEWATER SYSTEMS
(East Carolina University, 2013)
This study compares the phosphorus (P) treatment efficiency of on-site wastewater systems (OWS) and municipal wastewater treatment systems (MWS) and quantifies impacts each technology has on ground and surface water. ...
Modulation of IKKβ with AMPK Improves Insulin Sensitivity in Skeletal Muscle
(East Carolina University, 2008-11)
Activation of the insulin receptor substrate (IRS)-1 is necessary for proper transduction of the insulin signal. IRS-1 serine312(human)/307(rodent) phosphorylation, however, results in disruption of this signal and subsequent ...
Obese Children Have a Lower Lipolytic Response to an Acute Bout of Exercise When Compared to Lean
(East Carolina University, 2010)
Over 17% of American children are obese. These are epidemic proportions considering the associated risk of heart disease and Type 2 diabetes. Excess fat is caused from an imbalance in energy stored versus energy expended. ...
Regulation of Lipolysis By Perilipin : influence of Obesity and Exercise Training
(East Carolina University, 2010)
Obesity is the result of excess energy storage due to an imbalance between energy storage and energy utilization. Excess energy is stored as triacylglycerol (TAG) in adipose tissue in various regions throughout the body. ...
Effects of Parental Obesity on Fat Metabolism During Submaximal Exercise in Children
(East Carolina University, 2009)
The aim of the present study was to compare fat metabolism during submaximal exercise in children with a morbidly obese parent - (COP) (BMI [greater than or equal to] 40 kg/m²) to children with relatively lean parents - ...