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    AuthorBattaglia, Gina (1)Bennett, Hunter J. (1)Bollinger, Lance M. (1)Choplin, Eric Seneca (1)Ellis, Rocío Jazmin (1)Ernst, Jacob Matthew (1)Fisher-Wellman, Kelsey H. (1)Gavin, Kathleen M. (1)Henes, Sarah T. (1)Johnson, Emily Ann (1)... View MoreSubject
    Biology, Physiology (20)
    Physiology (20)
    Kinesiology (9)Obesity (6)Exercise (5)Mitochondria (5)Muscle proteins (4)Skeletal muscle (4)Aging (3)Biochemistry (3)... View MoreDate Issued2010 (5)2011 (5)2013 (5)2012 (4)2014 (1)Has File(s)
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    Effects of Insulin Sensitivity Modulators on the Mitochondrial Fate of Oxygen in Skeletal Muscle 

    Kane, Daniel A. (East Carolina University, 2010)
    Increasingly, reactive oxygen species (ROS) are implicated in the development of insulin resistance. To test the hypothesis that modulators of insulin sensitivity (i.e., metformin, ovarian sex steroids and exercise training) ...
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    A single dose of metformin improves whole body insulin sensitivity and alters cellular redox state in skeletal muscle of Zucker fa/fa rats 

    Lark, Daniel Stephen (East Carolina University, 2010)
    Energy balance is considered a fundamental requirement of life forms from single cell organisms to higher mammals such as humans. Unfortunately, our species has also discovered the detrimental metabolic responses to excess ...
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    Regulation of Lipolysis By Perilipin : influence of Obesity and Exercise Training 

    Johnson, Emily Ann (East Carolina University, 2010)
    Obesity is the result of excess energy storage due to an imbalance between energy storage and energy utilization. Excess energy is stored as triacylglycerol (TAG) in adipose tissue in various regions throughout the body. ...
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    IL-15 : A NOVEL REGULATOR OF LIPOLYSIS IN HUMANS? 

    Pierce, Joseph R., Jr. (East Carolina University, 2014)
    Interactions between and within organ systems such as skeletal muscle (SkM) and adipose tissue (AT), via immune cell signaling factors (cytokines), may regulate the development of obesity. The increased expression and ...
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    Effects of obesity on the transcriptional regulation of protein degradation in skeletal muscle 

    Bollinger, Lance M. (East Carolina University, 2013)
    Effects of obesity on the transcriptional regulation of protein degradation in skeletal muscle by Lance M. Bollinger November, 2013 Director of Thesis/Dissertation: Jeffrey J. Brault Major Department: Kinesiology ...
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    SKELETAL MUSCLE METABOLIC FLEXIBILITY IMPAIRMENTS IN RESPONSE TO LIPID WITH OBESITY : EFFECT OF EXERCISE TRAINING 

    Battaglia, Gina (East Carolina University, 2012)
    Obese individuals exhibit skeletal muscle metabolic inflexibility by failing to increase fat oxidation and genes linked with mitochondrial biogenesis in response to a high-fat diet (HFD) and lipid incubation in cell culture. ...
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    Proximal vs. Distal Fascicle Behavior within the Biceps Femoris Long Head at Different Muscle Activation Levels 

    Bennett, Hunter J. (East Carolina University, 2013)
    Hamstring strains have been shown to occur more often in the long head of the biceps femoris (BFLH) than the semitendinosus and semimembranosus, with most injuries occurring in the proximal half of the BFLH. Muscle modeling ...
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    The Region Specific Influence of Estradiol on In-Vivo Lipolysis in Subcutaneous Adipose Tissue in Overweight-to-Moderately-Obese Premenopausal Women 

    Gavin, Kathleen M. (East Carolina University, 2012)
    Premenopausal women demonstrate preferential accumulation of adiposity in the gynoid region, a distribution which shifts towards the abdominal region after the menopausal transition. Although estrogen is implicated as a ...
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    The effects of statins on mitochondrial function 

    Mayo, William Joseph (East Carolina University, 2013)
    Statins, or 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, are among the most commonly prescribed medications in the United States. They are commonly used to treat hypercholesterolemia, a condition ...
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    ESTABLISHMENT OF THE PYRUVATE DEHYDROGENASE COMPLEX AS A CENTRAL REGULATOR OF MITOCHONDRIAL REDOX WITHIN SKELETAL MUSCLE 

    Fisher-Wellman, Kelsey H. (East Carolina University, 2013)
    Once regarded as "byproducts" of aerobic metabolism, the production of superoxide/H₂O₂ is now understood to be a highly specialized and extensively regulated process responsible for exerting control over a vast number of ...
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