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THE EFFECTS OF CIRCADIAN RHYTHM ON INFLAMMATORY RESPONSE AND CYTOKINE LEVELS IN HEPATIC MACROPHAGES
(East Carolina University, 2014)
In mammals, many aspects of daily behavior and physiology such as the sleep-wake cycle, body temperature, and liver metabolism are regulated by endogenous circadian mechanisms. Despite tissue-specific physiological ...
NOVEL MECHANISMS GOVERNING SKELETAL MUSCLE MITOCHONDRIAL BIOENERGETICS : OXPHOS EFFICIENCY AND cAMP/PKA SIGNALING
(East Carolina University, 2014)
Understanding the regulation of cellular metabolism is paramount to treating the growing prevalence of metabolic disease worldwide. In cellular metabolism, mitochondrial oxidative phosphorylation (OXPHOS) plays a key role ...
EFFECT OF MENTOR-LED VIGOROUS AEROBIC EXERCISE PROGRAM ON BODY COMPOSITION, PEAK VO₂, AND INSULIN SENSITIVITY IN OVERWEIGHT AND OBESE ADOLESCENTS
(East Carolina University, 2014)
In the past few decades obesity rates in the US have reached epidemic proportions in both adults and children. Nearly one-third of American adults are obese, and since 1980, the obesity rates for children 6-11 years and ...