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Now showing items 111-120 of 210
Unravelling the mechanisms of menopause-induced insulin resistance: novel roles for estradiol in skeletal muscle mitochondrial function
(East Carolina University, 2016-11-16)
Menopause results in a progressive decline in ovarian production of 17[beta]-estradiol (E2), increased adiposity and a higher risk for type-2 diabetes, but hormone replacement therapies containing E2 reverse most of these ...
ELUCIDATION ON THE MECHANISM OF CAMKKα AS A PRO-GROWTH KINASE IN MOUSE SKELETAL MUSCLE
(East Carolina University, 2016-12-15)
Type 2 diabetes affects ~25 million people in the U.S., and is the primary cause of non-traumatic lower limb amputation and the leading cause of blindness in adults. Major risk factors for the development of type 2 diabetes ...