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The Effects of Aerobic Exercise Training in Children with Lean and Extremely Obese Biological Mothers
(East Carolina University, 2011)
The purpose of this study was to compare fat oxidation rates between children of lean biological mothers (CLP) (BMI[less than or equal to]28kg/m[superscript]2) and children of extremely obese biological mothers (COP) ...
EFFECTS OF A 16 WEEK PHYSICAL ACTIVITY INTERVENTION ON SERUM C-REACTIVE PROTEIN CONCENTRATIONS IN 8-11 YEAR OLD AFRICAN AMERICAN AND CAUCASIAN CHILDREN.
(East Carolina University, 2013)
C-reactive protein (CRP) is a non-specific marker of systemic inflammation that has been associated with heart disease, obesity, and metabolic disorders in adults and children. Previous physical activity interventions have ...
Effects of Insulin Sensitivity Modulators on the Mitochondrial Fate of Oxygen in Skeletal Muscle
(East Carolina University, 2010)
Increasingly, reactive oxygen species (ROS) are implicated in the development of insulin resistance. To test the hypothesis that modulators of insulin sensitivity (i.e., metformin, ovarian sex steroids and exercise training) ...
Deletion of the Protein Kinase A/Protein Kinase G Target SMTNL1 Promotes an Exercise-adapted Phenotype in Vascular Smooth Muscle
(East Carolina University, 2008-04-25)
In vivo protein kinases A and G (PKA and PKG) coordinately phosphorylate a broad range of substrates to mediate their various physiological effects. The functions of many of these substrates have yet to be defined genetically. ...
Factors Related to Objectively Measured Physical Activity in Preschool Children
(East Carolina University, 2009-05)
This study examined correlates of objectively measured physical activity (PA) in a diverse sample of preschool children (age 3–5 years; n=331). Accelerometer min·hr−1 of moderate-to-vigorous physical activity (MVPA) and ...
Metabolic Inflexibility in Skeletal Muscle With Obesity
(East Carolina University, 2009)
The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ...
Muscle Work Discrepancy during Incline and Decline Running at Three Speeds
(East Carolina University, 2009)
Introduction: Previous research has explored muscle function during gait and this work has shown that more positive mechanical muscle work is produced in gait tasks that primarily raise the center of mass (incline gait ...
Gender Differences in Aerobic and Work Capacity During Plantar Flexion Exercise
(East Carolina University, 2009)
Maximal oxygen consumption (VO2max) is lower in females compared to males during traditional whole body, systemic exercise. These differences in VO2max between men and women are still present even after correcting for ...
Comparison of Scaled vs. Ultrasound Based Musculoskeletal Models on Knee Muscle Moments During Single-Leg Squatting
(East Carolina University, 2012)
Muscles produce force, resulting in moments about a joint, causing movement of the body. Muscle forces are estimated with a Hill-type model incorporating four parameters; optimal fiber length (OFL), tendon slack length, ...
Influence of training history and contraction velocity on hamstring muscle coactivation during maximal effort knee extension
(East Carolina University, 2012)
When a muscle produces voluntary force, muscles on the opposite side of the joint, the antagonists, are also activated. While coactivation of the knee flexors during knee extension is presumed to increase joint stability ...