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Metabolic Inflexibility in Skeletal Muscle With Obesity
(East Carolina University, 2009)
The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ...
Mitochondrial Oxidative Capacity In Human Skeletal Muscle: Association with Plasma Lactate Concentration
(East Carolina University, 2018-07-11)
ABSTRACT Background: Metabolic disease is a growing concern for public health. Obesity and Type II Diabetes are an epidemic and a phenotype for insulin resistance in human skeletal muscle. A reduced mitochondrial function ...