Browsing Microbiology and Immunology by Subject "p53"

Now showing items 1-2 of 2

  • p53 and NGAL: dual regulatory roles in advanced prostate cancer 

    Chappell, William H. (East Carolina University, 2011)
    The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ...

  • Targeting prostate cancer based on signal transduction and cell cycle pathways 

    Lee, John T.; Lehmann, Brian D.; Terrian, David M.; Chappell, William H.; Stivala, Franca; Libra, Massimo; Martelli, Alberto M.; Steelman, Linda S.; McCubrey, James A. (East Carolina University, 2008-06-15)
    Prostate cancer remains a leading cause of death in men despite increased capacity to diagnose at earlier stages. After prostate cancer has become hormone independent, which often occurs after hormonal ablation therapies, ...