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Phylogeny and Classification of the Trapdoor Spider Genus : An Integrative Approach to Evaluating Taxonomic Hypotheses
(2010)
Background
Revised by Bond and Platnick in 2007, the trapdoor spider genus Myrmekiaphila comprises 11 species. Species delimitation and placement within one of three species groups was based on modifications of the male ...
Drosophila Ctf4 is essential for genome stability and normal cell cycle progression
(East Carolina University, 2010)
Proper DNA replication and well-timed cell cycle progression are vital to the normal functioning of a cell. Precise coordination between these mechanisms' constituent proteins ensures their processivity while safeguarding ...
Are Marine Migrations of Striped Bass Genetically Pre-determined? : An investigation of Albemarle Sound-Roanoke River Striped Bass Migratory Patterns
(East Carolina University, 2010)
Striped bass, Morone saxatilis, is one of the most thoroughly studied anadromous fish species in the United States, with records governing the management of the species dating back to the late 1600s. However, management ...
THE ROLE OF SDF-1[alpha] AS A VASCULOGENIC CHEMOKINE AND ENDOTHELIUM-ASSOCIATED CELL ADHESION MOLECULE FOR THE RECRUITMENT OF BONE MARROW-DERIVED PROGENITOR CELLS TO DEVELOPING TUMORS
(East Carolina University, 2010)
Tumor vascularization is an important control point in cancer progression and its inhibition is a promising approach to cancer therapy. Stromal-derived factor-1 alpha (SDF-1 alpha or CXCL12) is a chemoattractant for ...
Sld5, A Subunit of the Heterotetrameric GINS Complex is Necessary for Normal Cell Cycle Progression and Genomic Stability
(East Carolina University, 2010)
Sld5 is one component of the GINS heterotetrameric complex essential to DNA replication. Specifically, GINS is known for its integral role during the G1 to S phase transition in the cell cycle. The GINS complex is comprised ...
EXPLORING THE BYSTANDER EFFECT FOLLOWING VERY LOW DOSE RADIATION
(East Carolina University, 2010)
Bystander effects are defined as the phenomenon in which unirradiated cells respond biologically when their neighbors are irradiated. The exact mechanisms of these cellular responses are still not known, especially in ...