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Effect of MicroRNA-34c on Regenerative Axon Growth in Dorsal Root Ganglion Neurons of the Peripheral Nervous System
(East Carolina University, 2011)
The peripheral nervous system is unique in its ability to regenerate axons after injury. Our lab previously assessed the miRNA expression levels of the regenerating sciatic nerve which indicated miR-34c up-regulation. ...
Spatio-Temporal Expression of Chondroitin Sulfate Antigens in Early Chick Pituitary and Thyroid
(East Carolina University, 2012)
The chondroitin sulfate antigens d1C4 and TC2 have been hypothesized to play a role in cartilage differentiation in the limb and early morphogenesis of the heart in chick embryos. The antibody d1C4 recognizes a native ...
The Role of Mitochondrial Biogenesis in Human Mesenchymal Stem Cell Differentiation and Acquisition of a Cardiac Phenotype
(East Carolina University, 2013)
Introduction: With an increased understanding of myocardial infarction, human mesenchymal stem cell (hMSC) transplantation therapies have shown promising results as a possible treatment for heart failure. However, little ...
Distribution Patterns of Juvenile Spotted Seatrout (Cynoscion nebulosus) and Red Drum (Sciaenops ocellatus) Along Shallow Beach Habitats in Pamlico River, North Carolina
(East Carolina University, 2012)
The association of juvenile spotted seatrout (Cynoscion nebulosus) and red drum (Sciaenops ocellatus) with Submerged Aquatic Vegetation (SAV) is well documented. However, their association with other estuarine habitats ...
Characterizing Environmental and Physicochemical Conditions in Nursery Areas of River Herring in Chowan River, North Carolina
(East Carolina University, 2012)
Anadromous fishes such as blueback herring Alosa aestivalis and alewife A. pseudoharengus, utilize sounds, rivers, and tributaries during spawning. Collectively known as river herring, these two ecologically important ...
Anti-Cancer Activity of Cucurbitacin IIa
(East Carolina University, 2012)
Cancer is a debilitating disease resulting from uncontrolled proliferation. One major treatment strategy for cancer is the application of chemotherapeutic drugs which kill cancer cells. Cucurbitacins are a new family ...