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SPATIAL EXPRESSION OF MATRIX AND MATRIX RECEPTOR PROTEINS IN THE DEVELOPING SYNOVIAL JOINT
(East Carolina University, 2013)
Little is understood about the complex spatial and temporal molecular interactions necessary to form a fully functional synovial joint. Understanding molecular pathways and signaling within the developing joint continues ...
Inhibitory and oxidative effects of gossypol on MCF7 Breast Cancer cells in vitro
(East Carolina University, 2013)
Human cancer is the second leading cause of death in the United States and breast cancer is responsible for the second highest number of deaths in women with cancer worldwide. Today, cancer is becoming more and more ...
The Evolution of Organ Shape : Distal Tip Cell Migration and Gonadogenesis in Nematodes
(East Carolina University, 2013)
Animals display a variety of shapes in nature. The different shape of homologous organs allows them to adopt different functions and therefore, allows animals to live in different ecological niches. However, little is ...
Characterization of the Role of Mcm10 in DNA Replication in Drosophila melanogaster
(East Carolina University, 2013)
Replication of the genome and proper formation, and packaging, of chromatin are processes essential to eukaryotic life. Maintenance of epigenetic chromatin states is essential for faithfully reproducing the transcriptional ...
Citizen Science: Is It Worth Your Time?
(East Carolina University, 2015-12-17)
This dissertation investigated citizen science, a tool that connects the public to the scientific community through research-based projects and education campaigns. Benefits include volunteers adding data to long-term data ...
The genomes of two key bumblebee species with primitive eusocial organization
(2015-04-24)
Background
The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. ...
Elucidating the mechanisms of Nickel as an animal mutagen
(East Carolina University, 2016-04-28)
Nickel is an essential metal for many organisms. Nickel occurs naturally from volcanism and weathering of stone. Recently production of nickel from anthropogenic sources has overtaken natural production. Combustion of ...
Using Mosquitofish, Gambusia affinis, as Bioindicators for the presence of Endocrine Disrupting Compounds in Greenville's Wastewater Effluent
(2014)
Endocrine disrupting compounds (EDCs) are compounds that arise from an assortment of manufactured sources (plastics, pharmaceuticals, pulp mill waste), which have the potential to interrupt hormone pathways by mimicking ...
Conservation and Expression of SNF2 Proteins in Chondrus crispus
(2014)
The SNF2 families of ATP-dependent helicases are the central catalytic subunits for chromatin remodeling complexes. The most widely studied is the multisubunit SWI/SNF complex, which has been found in plants, yeast, and ...
Comparison of ZnO nanoparticles and ZnCl₂ induced germ cell apoptosis in Caenorhabditis elegans
(East Carolina University, 2014)
There is inadequate research data available on manufactured ZnO nanoparticles. Manufactured nanoparticles are widely used in various products and production of manufactured nanoparticles is becoming increasingly abundant. ...