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Characterization of Extracellular Polymeric Substances from Acidophilic Microbial Biofilms
(East Carolina University, 2010-05)
We examined the chemical composition of extracellular polymeric substances (EPS) extracted from two natural microbial pellicle biofilms growing on acid mine drainage (AMD) solutions. The EPS obtained from a mid-developmental-stage ...
Repair of Clustered DNA Lesions in Double Strand Break Repair Deficient Human Tumor Cells
(East Carolina University, 2010)
DNA-dependent protein kinase (DNA-PK) is a holoenzyme of three subunits, Ku70, Ku80, and the DNA-Pk catalytic subunit (DNA-PKcs). DNA-PK serves a role in non-homologous end joining to repair double stranded breaks, and ...
Phylogeny and Classification of the Trapdoor Spider Genus : An Integrative Approach to Evaluating Taxonomic Hypotheses
(2010)
Background
Revised by Bond and Platnick in 2007, the trapdoor spider genus Myrmekiaphila comprises 11 species. Species delimitation and placement within one of three species groups was based on modifications of the male ...
Connecting Mutations of the RNA Polymerase II C-Terminal Domain to Complex Phenotypic Changes Using Combined Gene Expression and Network Analyses
(2010)
The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is essential for mRNA synthesis and processing, through coordination of an astounding array of protein-protein interactions. ...
Acute effects of fine particulate air pollution on ST segment height: A longitudinal study
(2010)
Background
The mechanisms for the relationship between particulate air pollution and cardiac disease are not fully understood. Air pollution-induced myocardial ischemia is one of the potentially important mechanisms.
...
Deep sequencing identifies novel and conserved microRNAs in peanuts (L.)
(2010)
Background
MicroRNAs (miRNAs) are a new class of small, endogenous RNAs that play a regulatory role in the cell by negatively affecting gene expression at the post-transcriptional level. miRNAs have been shown to control ...
Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective
(2010)
Background
There is very small occurrence of adenocarcinoma in the small bowel. We present a case of primary duodenal adenocarcinoma and discuss the findings of the case diagnostic modalities, current knowledge on the ...
Drosophila Ctf4 is essential for genome stability and normal cell cycle progression
(East Carolina University, 2010)
Proper DNA replication and well-timed cell cycle progression are vital to the normal functioning of a cell. Precise coordination between these mechanisms' constituent proteins ensures their processivity while safeguarding ...
Are Marine Migrations of Striped Bass Genetically Pre-determined? : An investigation of Albemarle Sound-Roanoke River Striped Bass Migratory Patterns
(East Carolina University, 2010)
Striped bass, Morone saxatilis, is one of the most thoroughly studied anadromous fish species in the United States, with records governing the management of the species dating back to the late 1600s. However, management ...
THE ROLE OF SDF-1[alpha] AS A VASCULOGENIC CHEMOKINE AND ENDOTHELIUM-ASSOCIATED CELL ADHESION MOLECULE FOR THE RECRUITMENT OF BONE MARROW-DERIVED PROGENITOR CELLS TO DEVELOPING TUMORS
(East Carolina University, 2010)
Tumor vascularization is an important control point in cancer progression and its inhibition is a promising approach to cancer therapy. Stromal-derived factor-1 alpha (SDF-1 alpha or CXCL12) is a chemoattractant for ...