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DERIVATION OF TOLEROGENIC THERAPEUTIC VACCINES FOR MOUSE MODELS OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
(East Carolina University, 2012)
Multiple sclerosis (MS) is a chronic inflammatory disease that results in autoimmune demyelination of the human central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a widely-studied animal ...
Biogeographic Characterization of Fishes from Intertidal Sandflats in Pamlico River, North Carolina
(East Carolina University, 2012)
The spatial and temporal changes in fish community structure in Pamlico River, North Carolina were analyzed. Salinity and temperature are important water quality parameters influencing fish community structure in estuaries. ...
Food and feeding habits of the spiny dogfish Squalus acanthias overwintering off the coast of North Carolina and the effects on the marine community
(East Carolina University, 2012)
Spiny dogfish (Squalus acanthias) are small, highly migratory sharks that occur in large numbers in North Carolina nearshore waters between November and March. This species has long been considered a pest by commercial ...
Characterizing the vegetative phenotype of fzt maize mutant
(East Carolina University, 2012)
microRNAs are short, non-coding RNA strands that regulate gene expression post-transcriptionally in all multicellular organisms. miRNAs begin as a hairpin in the nucleus. The primary miRNA (pri-miRNA) and preliminary ...
Millipede Taxonomy after 250 Years: Classification and Taxonomic Practices in a Mega-Diverse yet Understudied Arthropod Group
(2012)
Background
The arthropod class Diplopoda is a mega-diverse group comprising >12,000 described millipede species. The history of taxonomic research within the group is tumultuous and, consequently, has yielded a questionable ...
Ancient gene transfer from algae to animals: Mechanisms and evolutionary significance
(2012)
Background
Horizontal gene transfer (HGT) is traditionally considered to be rare in multicellular eukaryotes such as animals. Recently, many genes of miscellaneous algal origins were discovered in choanoflagellates. ...
Digits Lost or Gained? Evidence for Pedal Evolution in the Dwarf Salamander Complex ( Plethodontidae)
(2012)
Change in digit number, particularly digit loss, has occurred repeatedly over the evolutionary history of tetrapods. Although digit loss has been documented among distantly related species of salamanders, it is relatively ...
MicroRNA Expression Analysis in the Cellulosic Biofuel Crop Switchgrass () under Abiotic Stress
(2012)
Switchgrass has increasingly been recognized as a dedicated biofuel crop for its broad adaptation to marginal lands and high biomass. However, little is known about the basic biology and the regulatory mechanisms of gene ...
Widespread impact of horizontal gene transfer on plant colonization of land
(2012-10)
In complex multicellular eukaryotes such as animals and plants, horizontal gene transfer is commonly considered rare with very limited evolutionary significance. Here we show that horizontal gene transfer is a dynamic ...
Habitat and Scale Shape the Demographic Fate of the Keystone Sea Urchin in Mediterranean Macrophyte Communities
(2012)
Demographic processes exert different degrees of control as individuals grow, and in species that span several habitats and spatial scales, this can influence our ability to predict their population at a particular ...