On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study
Li, Taoran; Zhu, Xiaofeng; Thongphiew, Danthai; Lee, W. Robert; Vujaskovic, Zeljko; Wu, Qiuwen; Yin, Fang-Fang; Wu, Q. Jackie
The purpose of this paper is to evaluate the feasibility and clinical dosimetric benefit of an on-line, that is, with the patient in the treatment position, Adaptive Radiation Therapy (ART) system for prostate cancer treatment based on daily cone-beam CT imaging and fast volumetric reoptimization of treatment plans. A fast intensity-modulated radiotherapy (IMRT) plan reoptimization algorithm is implemented and evaluated with clinical cases. The quality of these adapted plans is compared to the corresponding new plans generated by an experienced planner using a commercial treatment planning system and also evaluated by an in-house developed tool estimating achievable dose-volume histograms (DVHs) based on a database of existing treatment plans. In addition, a clinical implementation scheme for ART is designed and evaluated using clinical cases for its dosimetric qualities and efficiency.
Li, Taoran, & Zhu, Xiaofeng, & Thongphiew, Danthai, & Lee, W. Robert, & Vujaskovic, Zeljko, & Wu, Qiuwen, & Yin, Fang-Fang, & Wu, Q. Jackie. (January 2010). On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study. Journal of Oncology, (1-12. Retrieved from http://hdl.handle.net/10342/5741
Li, Taoran, and Zhu, Xiaofeng, and Thongphiew, Danthai, and Lee, W. Robert, and Vujaskovic, Zeljko, and Wu, Qiuwen, and Yin, Fang-Fang, and Wu, Q. Jackie. "On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study". Journal of Oncology. . (1-12.), January 2010. April 19, 2021. http://hdl.handle.net/10342/5741.
Li, Taoran and Zhu, Xiaofeng and Thongphiew, Danthai and Lee, W. Robert and Vujaskovic, Zeljko and Wu, Qiuwen and Yin, Fang-Fang and Wu, Q. Jackie, "On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study," Journal of Oncology 2010, no. (January 2010), http://hdl.handle.net/10342/5741 (accessed April 19, 2021).
Li, Taoran, Zhu, Xiaofeng, Thongphiew, Danthai, Lee, W. Robert, Vujaskovic, Zeljko, Wu, Qiuwen, Yin, Fang-Fang, Wu, Q. Jackie. On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study. Journal of Oncology. January 2010; 2010() 1-12. http://hdl.handle.net/10342/5741. Accessed April 19, 2021.