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TLR5 participates in the TLR4 receptor complex and promotes MyD88- dependent signaling in environmental lung injury
(2020-01-28)
Lung disease causes significant morbidity and mortality, and is exacerbated by environmental injury, for example through lipopolysaccharide (LPS) or ozone (O3). Toll-like receptors (TLRs) orchestrate immune responses to ...
Understanding Racial Disparities in Exposure to Traffic-Related Air Pollution: Considering the Spatiotemporal Dynamics of Population Distribution
(2020-02-01)
This study investigates the effect of spatiotemporal distributions of racial groups on
disparities in exposure to traffic-related air pollution by considering people’s daily movement
patterns. Due to human mobility, a ...
The Proton-Sensing GPR4 Receptor Regulates Paracellular Gap Formation and Permeability of Vascular Endothelial Cells
(2020-02-21)
be activated by protons in the inflamed tissue microenvironment. Herein, we report that acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelialcells through the ...
COMPARING THE EFFECT OF COMMUNITY ENGAGEMENT ON WATER FILTER USAGE IN RURAL GUATEMALA
(East Carolina University, 2021-05-28)
Abstract
Purpose: The purpose of the study was to compare the effect of a community engagement (CE) strategy on sustainability of a safe drinking water initiative.
Methods: A natural, quasi-experimental study design was ...
Designing A Research Study on ECU’s Recycling Habits Through Prototyping, Pivoting, and Failing
(East Carolina University, 2021-05-28)
According to the National Waste and Recycling Association, approximately 25% of items in recycling bins are considered nonrecyclable contamination, obstructing recycling efforts nationwide. On ECU’s campus, contamination ...
TELLUS: A BUSINESS DRIVING THE WORLD’S TRANSITION TO SUSTAINABLE PRODUCTS
(East Carolina University, 2021-05-28)
Tellus is a business founded in the HNRS 2000/3000 courses with a mission of driving
the world’s transition to eco-friendly products. Initially, Tellus targeted the waste generated by
plastics in the medical field, such ...
DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial
(2021-07-12)
Aberrant DNA methylation profiles have been implicated in numerous cardiovascular diseases; however, few studies have investigated how these epigenetic modifications contribute to stroke recurrence. The aim of this study ...
A Bayesian machine scientist to aid in the solution of challenging scientific problems
(2020-01-31)
Closed-form, interpretable mathematical models have been instrumental for advancing our understanding of the world; with the data revolution, we may now be in a position to uncover new such models for many systems from ...
Engaging with Library Staff: Lessons from a Staff Assembly
(2020-06-17)
East Carolina University’s J.Y. Joyner Library provides its employees with the opportunity to have their voice heard and impact the direction of the library by engaging its staff assemblies. The current SHRA Executive ...
Developing Concept Enriched Models for Big Data Processing Within the Medical Domain
(2020-07)
Within the past few years, the medical domain has endeavored to incorporate artificial intelligence, including cognitive computing tools, to develop enriched models for processing and synthesizing knowledge from Big Data. ...