Search
Now showing items 71-80 of 173
Strongly interacting matter under rotation
(2018-02-02)
The vorticity-driven effects are systematically studied in various aspects. With AMPT the distributions of vorticity has been investigated in heavy ion collisions with different collision parameters. Taking the rotational ...
Spontaneous bile duct perforation in a neonate
(2018-08-14)
We present a case of spontaneous biliary perforation (SBP) in a previously healthy 3-week-old boy with wor- sening scleral icterus, abdominal distension, and acholic stools. Abdominal ultrasound demonstrated moderate ascites ...
Bacteroides fragilis requires the ferrous-iron transporter FeoAB and the CobN-like proteins BtuS1 and BtuS2 for assimilation of iron released from heme
(2018-05-07)
The intestinal commensal and opportunistic anaerobic pathogen Bacteroides fragilis has an essential requirement for both heme and free iron to support growth in extraintestinal infections. In the absence of free iron, B. ...
Step-wise evolution of complex chemical defenses in millipedes: a phylogenomic approach
(2018-02-16)
With fossil representatives from the Silurian capable of respiring atmospheric oxygen, millipedes
are among the oldest terrestrial animals, and likely the first to acquire diverse and complex chemical defenses against ...
Stem cell models of human synapse development and degeneration
(2018-11-26)
Many brain disorders exhibit altered synapse formation in development or syn- apse loss with age. To understand the complexities of human synapse development and degeneration, scientists now engineer neurons and brain ...
The effects of exercise on hypothalamic neurodegeneration of Alzheimer’s disease mouse model
(2018-01-02)
Alzheimer’s disease is a neurodegenerative disorder that affects the central nervous sys- tem. In this study, we characterized and examined the early metabolic changes in the triple transgenic mouse AD model (3xtg-AD), and ...
Cutaneous adverse reactions in B-RAF positive metastatic melanoma following sequential treatment with B-RAF/MEK inhibitors and immune checkpoint blockade or vice versa. A single-institutional case-series
(2018-12-16)
Background
With the advent of immune-checkpoint inhibitors and targeted treatments (TT), there have been unprecedented response rates and survival in advanced melanoma, but the optimal sequencing of these two treatments ...
Venous varices of the heart: a case report of spontaneous coronary sinus thrombosis with persistent left superior vena cava
(2018-08-16)
Absence of coronary sinus (CS) ostium and presence of a persistent superior left vena cava (PLSVC) are rare congenital anomalies.1 We report a case of spontaneous CS thrombosis with PLSVC associated with new-onset atrial ...
TEAM-UP for quality: a cluster randomized controlled trial protocol focused on preventing pressure ulcers through repositioning frequency and precipitating factors
(2018-02-20)
Background: Pressure ulcers/injuries (PrUs), a critical concern for nursing homes (NH), are responsible for chronic wounds, amputations, septic infections, and premature deaths. PrUs occur most commonly in older adults and ...
The 3-Phosphoinositide-Dependent Protein Kinase 1 Inhibits Rod Photoreceptor Development
(2018-10-10)
The transition of rod precursor cells to post-mitotic rod photoreceptors can be promoted by extrinsic factors such as insulin-like growth factor 1 (IGF- 1), which regulates phosphatidylinositide concentration, and consequently ...