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Patterns of pelvic radiotherapy in patients with stage II/III rectal cancer
(2013-10-02)
High-level evidence supports adjuvant radiotherapy for rectal cancer. We examined the influence of sociodemographic factors on patterns of adjuvant radiotherapy for resected Stage II/III rectal cancer. Methods. Patients ...
Social media guidelines and best practices - Recommendations from the council of residency directors (cord) social media taskforce
(2013-07-02)
Social media has become a staple of everyday life among over one billion people worldwide. A social networking presence has become a hallmark of vibrant and transparent communications. It has quickly become the preferred ...
Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
(2013-04-04)
There has been increasing recognition that the second-generation antipsychotic drugs can produce extrapyramidal side effects. This case reports the development of severe akathisia in a patient being treated with ziprasidone ...
All's well that begins Wells: Celebrating 60 years of Animal Behaviour and 36 years of research on anuran social behaviour
(2012-12-04)
The scientific study of frogs and toads as important systems in behavioural ecology traces its roots to an influential review published in this journal 36 years ago (Wells 1977a, ‘The social behaviour of anuran amphibians’, ...
Theoretical aspects and modelling of cellular decision making, cell killing and information-processing in photodynamic therapy of cancer
(2013-09-03)
Background: The aim of this report is to provide a mathematical model of the mechanism for making binary fate decisions about cell death or survival, during and after Photodynamic Therapy (PDT) treatment, and to supply the ...
Deep Sequencing Reveals Transcriptome Re-Programming of Taxus × media Cells to the Elicitation with Methyl Jasmonate
(2013-04-30)
Background Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. ...
Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
(2013-12-05)
The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection ...
Feasibility of Frequent Patient-Reported Outcome Surveillance in Patients Undergoing Hematopoietic Cell Transplantation
(2012-11-19)
Patient-reported outcomes (PROs), including symptoms and health-related quality of life (HRQOL), provide a patient-centered description of hematopoietic cell transplantation (HCT)-related toxicity. These data characterize ...
Daily precipitation distributions over the intra-Americas sea and their interannual variability
(2012-05-30)
The seasonal (March to October) and interannual variability of the cumulative distribution function (CDF) of precipitation is examined for Meso-America, the eastern Pacific and western Atlantic, commonly referred to as the ...