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Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells
(2014)
Hepatocellular carcinoma (HCC) is characterized by limited response to current
drug therapies. Here, we report that SC66, a novel AKT inhibitor, reduced cell viability
in a dose- and time-dependent manner, inhibited ...
Osteomyelitis Infection of Mycobacterium marinum: A Case Report and Literature Review
(2014-12)
Mycobacterium marinum (M. marinum) is a ubiquitous waterborne organism that grows optimally at temperatures around 30°C. It is a nontuberculous Mycobacterium found in nonchlorinated water with worldwide prevalence. It is ...
The dicer-like1 Homolog fuzzy tassel Is Required for the Regulation of Meristem Determinacy in the Inflorescence and Vegetative Growth in Maize
(2014-12)
Plant architecture is determined by meristems that initiate leaves during vegetative development and flowers during reproductive development. Maize (Zea mays) inflorescences are patterned by a series of branching events, ...
Introduction: Biology and the Idea of Culture
(2014)
This chapter analyses Frankenstein's dramatization of the costs and consequences of the drive for transcendence in terms of humanist culture's anxieties about human and nonhuman identities in capitalist production. The ...
Advancing research on racial-ethnic health disparities: Improving measurement equivalence in studies with diverse samples
(2014)
To conduct meaningful, epidemiologic research on racial-ethnic health disparities, racial-ethnic samples must be rendered equivalent on other social status and contextual variables via statistical controls of those extraneous ...
Challenges to adaptation: a fundamental concept for the shared socio-economic pathways and beyond
(2014)
The framework for the new scenarios being developed for climate research calls
for the development of a set of Shared Socioeconomic Pathways (SSPs), which are meant to
differ in terms of their challenges to mitigation ...
Brachial Flow-Mediated Dilation and Incident Atrial Fibrillation The Multi-Ethnic Study of Atherosclerosis
(2014)
Objective—It is unknown whether endothelial dysfunction precedes atrial fibrillation (AF) development. The objective of
this study was to examine the association of brachial flow-mediated dilation (FMD) with incident ...
Analysis of the B-RAFV600E mutation in cutaneous melanoma patients with occupational sun exposure
(2014)
Sun-exposure is one of the risk factors associated with the development of a cutaneous neoplasm. In melanoma, the Ras-Raf-MEK-ERK (MAPK) signaling pathway is constitutively activated through multiple mechanisms, including ...